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A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes

Publication: Journal Article

Mauvais-Jarvis, Virkamaki, Michael, Winnay, Zisman, Kulkarni, and Kahn. 2000. “A Model to Explore the Interaction Between Muscle Insulin Resistance and Beta-Cell Dysfunction in the Development of Type 2 Diabetes”. Diabetes 49 (12): 2126-34.

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

Publication: Journal Article

Ueki, Algenstaedt, Mauvais-Jarvis, and Kahn. 2000. “Positive and Negative Regulation of Phosphoinositide 3-Kinase-Dependent Signaling Pathways by Three Different Gene Products of the P85alpha Regulatory Subunit”. Mol Cell Biol 20 (21): 8035-46.

Cellular compartmentalization in insulin action: altered signaling by a lipid-modified IRS-1

Publication: Journal Article

Kriauciunas, Myers, and Kahn. 2000. “Cellular Compartmentalization in Insulin Action: Altered Signaling by a Lipid-Modified IRS-1”. Mol Cell Biol 20 (18): 6849-59.

Citation for the 2000 Roy O. Greep Award Lecture of The Endocrine Society to Dr. Christin Carter-Su

Publication: Journal Article

Kahn. 2000. “Citation for the 2000 Roy O. Greep Award Lecture of The Endocrine Society to Dr. Christin Carter-Su”. Endocr Rev 21 (4): 452-3.

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

Publication: Journal Article

Fasshauer, Klein, Ueki, Kriauciunas, Benito, White, and Kahn. 2000. “Essential Role of Insulin Receptor Substrate-2 in Insulin Stimulation of Glut4 Translocation and Glucose Uptake in Brown Adipocytes”. J Biol Chem 275 (33): 25494-501.

Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts

Publication: Journal Article

Winnay, Brüning, Burks, and Kahn. 2000. “Gab-1-Mediated IGF-1 Signaling in IRS-1-Deficient 3T3 Fibroblasts”. J Biol Chem 275 (14): 10545-50.

Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies

Publication: Journal Article

Goldfine, AB, Patti, Zuberi, Goldstein, LeBlanc, Landaker, Jiang, Willsky, and Kahn. 2000. “Metabolic Effects of Vanadyl Sulfate in Humans With Non-Insulin-Dependent Diabetes Mellitus: In Vivo and in Vitro Studies”. Metabolism 49 (3): 400-10.

Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice

Publication: Journal Article

Gazdag, Dumke, Kahn, and Cartee. 1999. “Calorie Restriction Increases Insulin-Stimulated Glucose Transport in Skeletal Muscle from IRS-1 Knockout Mice”. Diabetes 48 (10): 1930-6.

Diabetes. Causes of insulin resistance

Publication: Journal Article

Kahn. 1995. “Diabetes. Causes of Insulin Resistance”. Nature 373 (6513): 384-5.

A mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation

Publication: Journal Article

Ouwens, Zon, Pronk, Bos, Möller, Cheatham, Kahn, and Maassen. 1994. “A Mutant Insulin Receptor Induces Formation of a Shc-Growth Factor Receptor Bound Protein 2 (Grb2) Complex and P21ras-GTP Without Detectable Interaction of Insulin Receptor Substrate 1 (IRS1) With Grb2. Evidence for IRS1-Independent P21ras-GTP Formation”. J Biol Chem 269 (52): 33116-22.