Cellular bioenergetics as a target for obesity therapy
Tseng, Yu-Hua, Aaron Cypess, and Ronald Kahn. 2010. “Cellular Bioenergetics As a Target for Obesity Therapy”. Nat Rev Drug Discov 9 (6): 465-82.
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Absence of insulin signalling in skeletal muscle is associated with reduced muscle mass and function: evidence for decreased protein synthesis and not increased degradation
O’Neill, Elaine, John Wilding, Ronald Kahn, Holly Van Remmen, Anne McArdle, Malcolm Jackson, and Graeme Close. 2010. “Absence of Insulin Signalling in Skeletal Muscle Is Associated With Reduced Muscle Mass and Function: Evidence for Decreased Protein Synthesis and Not Increased Degradation”. Age (Dordr) 32 (2): 209-22.
Transplantation of adipose tissue and stem cells: role in metabolism and disease
Tran, Thien, and Ronald Kahn. 2010. “Transplantation of Adipose Tissue and Stem Cells: Role in Metabolism and Disease”. Nat Rev Endocrinol 6 (4): 195-213.
High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention: response to Thamer et al
Bluher, Matthias, Michael Stumvoll, Ronald Kahn, and Michael Ristow. 2010. “High Baseline Vitamin C Levels Do Not Prevent a Positive Outcome of a Lifestyle Intervention: Response to Thamer et Al”. Diabetes Care 33 (1): e17; author reply e18.
Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy
Ikeda, Hiroyuki, Ichiro Shiojima, Yukako Ozasa, Masashi Yoshida, Martin Holzenberger, Ronald Kahn, Kenneth Walsh, Takashi Igarashi, Dale Abel, and Issei Komuro. 2009. “Interaction of Myocardial Insulin Receptor and IGF Receptor Signaling in Exercise-Induced Cardiac Hypertrophy”. J Mol Cell Cardiol 47 (5): 664-75.
Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance
Sajan, Standaert, Rivas, Miura, Kanoh, Soto, Taniguchi, Kahn, and Farese. 2009. “Role of Atypical Protein Kinase C in Activation of Sterol Regulatory Element Binding Protein-1c and Nuclear Factor Kappa B (NFkappaB) in Liver of Rodents Used As a Model of Diabetes, and Relationships to Hyperlipidaemia and Insulin Resistance”. Diabetologia 52 (6): 1197-207.
Identification and importance of brown adipose tissue in adult humans
Cypess, Aaron, Sanaz Lehman, Gethin Williams, Ilan Tal, Dean Rodman, Allison Goldfine, Frank Kuo, et al. 2009. “Identification and Importance of Brown Adipose Tissue in Adult Humans”. N Engl J Med 360 (15): 1509-17.
A patient with type B insulin resistance syndrome, responsive to immune therapy
Page, Kathleen, Stephanie Dejardin, Ronald Kahn, Rohit Kulkarni, Kevan Herold, and Silvio Inzucchi. 2007. “A Patient With Type B Insulin Resistance Syndrome, Responsive to Immune Therapy”. Nat Clin Pract Endocrinol Metab 3 (12): 835-40.
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes
Pospisilik, Andrew, Claude Knauf, Nicholas Joza, Paule Benit, Michael Orthofer, Patrice Cani, Ingo Ebersberger, et al. 2007. “Targeted Deletion of AIF Decreases Mitochondrial Oxidative Phosphorylation and Protects from Obesity and Diabetes”. Cell 131 (3): 476-91.
Mitochondrial proton leak in obesity-resistant and obesity-prone mice
Fink, Brian, Judy Herlein, Katrine Almind, Saverio Cinti, Ronald Kahn, and William Sivitz. 2007. “Mitochondrial Proton Leak in Obesity-Resistant and Obesity-Prone Mice”. Am J Physiol Regul Integr Comp Physiol 293 (5): R1773-80.