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Ziqing (Leslie) Wang

Person: Postdoctoral Fellow

Dr. Wang earned her PhD from University of Delaware studying complex traits in poultry via omics applications. Her current research aims to crack the riddle of sleep and cognitive aging from the perspective of epigenetic and multi-omics markers. Outside of work, she’s into detective and mystery...

Objectively regular sleep patterns and mortality in a prospective cohort: The Multi-Ethnic Study of Atherosclerosis.

Publication: Journal Article

Chung, Joon, Matthew O Goodman, Tianyi Huang, Cecilia Castro-Diehl, Jarvis T Chen, Tamar Sofer, Suzanne M Bertisch, Shaun M Purcell, and Susan Redline. 2024. “Objectively Regular Sleep Patterns and Mortality in a Prospective Cohort: The Multi-Ethnic Study of Atherosclerosis.”. Journal of Sleep Research 33 (1): e14048.

Genome-wide association analysis of composite sleep health scores in 413,904 individuals.

Publication: Journal Article

Goodman, Matthew O, Tariq Faquih, Valentina Paz, Pavithra Nagarajan, Jacqueline M Lane, Brian Spitzer, Matthew Maher, et al. 2024. “Genome-Wide Association Analysis of Composite Sleep Health Scores in 413,904 Individuals.”. MedRxiv : The Preprint Server for Health Sciences.

Blood metabolites predicting mild cognitive impairment in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).

Publication: Journal Article

He, Shan, Einat Granot-Hershkovitz, Ying Zhang, Jan Bressler, Wassim Tarraf, Bing Yu, Tianyi Huang, et al. 2022. “Blood Metabolites Predicting Mild Cognitive Impairment in the Study of Latinos-Investigation of Neurocognitive Aging (HCHS/SOL).”. Alzheimer’s & Dementia (Amsterdam, Netherlands) 14 (1): e12259.

Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.

Publication: Journal Article

Wang, Heming, Nuzulul Kurniansyah, Brian E Cade, Matthew O Goodman, Han Chen, Daniel J Gottlieb, Sina A Gharib, et al. 2022. “Upregulated Heme Biosynthesis Increases Obstructive Sleep Apnea Severity: A Pathway-Based Mendelian Randomization Study.”. Scientific Reports 12 (1): 1472.

Recommendations on the use and reporting of race, ethnicity, and ancestry in genetic research: Experiences from the NHLBI TOPMed program.

Publication: Journal Article

Khan, Alyna T, Stephanie M Gogarten, Caitlin P McHugh, Adrienne M Stilp, Tamar Sofer, Michael L Bowers, Quenna Wong, et al. 2022. “Recommendations on the Use and Reporting of Race, Ethnicity, and Ancestry in Genetic Research: Experiences from the NHLBI TOPMed Program.”. Cell Genomics 2 (8).

Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations.

Publication: Journal Article

Elgart, Michael, Genevieve Lyons, Santiago Romero-Brufau, Nuzulul Kurniansyah, Jennifer A Brody, Xiuqing Guo, Henry J Lin, et al. 2022. “Non-Linear Machine Learning Models Incorporating SNPs and PRS Improve Polygenic Prediction in Diverse Human Populations.”. Communications Biology 5 (1): 856.

Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition.

Publication: Journal Article

Granot-Hershkovitz, Einat, Shan He, Jan Bressler, Bing Yu, Wassim Tarraf, Casey M Rebholz, Jianwen Cai, et al. 2023. “Plasma Metabolites Associated With Cognitive Function across Race/Ethnicities Affirming the Importance of Healthy Nutrition.”. Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association 19 (4): 1331-42.

Polygenic risk scores and kidney traits in the Hispanic/Latino population: The Hispanic Community Health Study/Study of Latinos.

Publication: Journal Article

Zhou, Laura Y, Tamar Sofer, Andrea R R Horimoto V, Gregory A Talavera, James P Lash, Jianwen Cai, and Nora Franceschini. 2023. “Polygenic Risk Scores and Kidney Traits in the Hispanic/Latino Population: The Hispanic Community Health Study/Study of Latinos.”. HGG Advances 4 (2): 100177.

Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex.

Publication: Journal Article

Sofer, Tamar, Nuzulul Kurniansyah, Michael Murray, Yuk-Lam Ho, Erik Abner, Tõnu Esko, Estonian Biobank Research Team, et al. 2023. “Genome-Wide Association Study of Obstructive Sleep Apnoea in the Million Veteran Program Uncovers Genetic Heterogeneity by Sex.”. EBioMedicine 90: 104536.