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123 results found

A parametric bootstrap approach for computing confidence intervals for genetic correlations with application to genetically-determined protein-protein networks.

Publication: Journal Article

Tsai, Yi-Ting, Yana Hrytsenko, Michael Elgart, Usman Tahir, Zsu-Zsu Chen, James G Wilson, Robert Gerszten, and Tamar Sofer. 2023. “A Parametric Bootstrap Approach for Computing Confidence Intervals for Genetic Correlations With Application to Genetically-Determined Protein-Protein Networks.”. MedRxiv : The Preprint Server for Health Sciences.

A polygenic risk score for Alzheimer's disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S.

Publication: Journal Article

Sofer, Tamar, Nuzulul Kurniansyah, Einat Granot-Hershkovitz, Matthew O Goodman, Wassim Tarraf, Iris Broce, Richard B Lipton, et al. 2023. “A Polygenic Risk Score for Alzheimer’s Disease Constructed Using APOE-Region Variants Has Stronger Association Than APOE Alleles With Mild Cognitive Impairment in Hispanic/Latino Adults in the U.S.”. Alzheimer’s Research & Therapy 15 (1): 146.

AFA: Ancestry-specific allele frequency estimation in admixed populations: The Hispanic Community Health Study/Study of Latinos.

Publication: Journal Article

Granot-Hershkovitz, Einat, Quan Sun, Maria Argos, Hufeng Zhou, Xihong Lin, Sharon R Browning, and Tamar Sofer. 2022. “AFA: Ancestry-Specific Allele Frequency Estimation in Admixed Populations: The Hispanic Community Health Study/Study of Latinos.”. HGG Advances 3 (2): 100096.

Xinye Qiu

Person: Postdoctoral Research Fellow

Dr. Xinye Qiu is a postdoctoral researcher working with Dr. Tamar Sofer. She received her Ph.D. degree in Population Health Sciences from Harvard T.H. Chan School of Public Health with a focus on environmental epidemiology. Her research is interdisciplinary and combines knowledge/skills across the...

Mengran Zhang

Person: Biostatistician/Master's student

I worked as a statistical analyst and bioinformatician in Dr. Sofer’s lab at Brigham & Women’s Hospital and I concentrated on a genetic survey project while working in the lab. I received my bachelor degree in Mathematics and Economics from Syracuse University and the master degree of Statistics &...

Danielle A Wallace

Person: Postdoctoral Fellow

Dr. Wallace is a Postdoctoral Research Fellow interested in understanding how environmental exposures, such as light and temperature, affect chrono-health in the general population. Her current research in the Sofer lab integrates data from wearable devices (such as actigraphy) with ‘omics data...

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

Publication: Journal Article

Suzuki, Ken, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Kim M Lorenz, Ravi Mandla, et al. 2024. “Genetic Drivers of Heterogeneity in Type 2 Diabetes Pathophysiology.”. Nature 627 (8003): 347-57.

Rest-activity rhythms across the lifespan: cross-sectional findings from the US representative National Health and Nutrition Examination Survey.

Publication: Journal Article

Wallace, Danielle A, Dayna A Johnson, Susan Redline, Tamar Sofer, and Joe Kossowsky. 2023. “Rest-Activity Rhythms across the Lifespan: Cross-Sectional Findings from the US Representative National Health and Nutrition Examination Survey.”. Sleep 46 (11).

Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL.

Publication: Journal Article

Justice, Anne E, Kristin Young, Stephanie M Gogarten, Tamar Sofer, Misa Graff, Shelly Ann M Love, Yujie Wang, et al. 2021. “Genome-Wide Association Study of Body Fat Distribution Traits in Hispanics/Latinos from the HCHS/SOL.”. Human Molecular Genetics 30 (22): 2190-2204.

Benchmarking association analyses of continuous exposures with RNA-seq in observational studies.

Publication: Journal Article

Sofer, Tamar, Nuzulul Kurniansyah, François Aguet, Kristin Ardlie, Peter Durda, Deborah A Nickerson, Joshua D Smith, et al. 2021. “Benchmarking Association Analyses of Continuous Exposures With RNA-Seq in Observational Studies.”. Briefings in Bioinformatics 22 (6).