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Quadri Adewale

he/him
Quadri joined the lab as a postdoctoral fellow in November 2024 to develop integrative models for studying the roles of coding and non-coding RNAs in resilience to Alzheimer's disease. He has a PhD in neuroscience from McGill University, Canada; an MSc in Control and Systems Engineering from the...

Welcome Alice Rodriguez!

Alice has joined the lab to help us better understand the contribution of exosomal miRNAs to elucidating progression and resilience against Alzheimer's disease pathology.

Pathway Network Tools

PxN - Pathway Networks (2025 Release) Github PCxN - Pathway co-expression network (2018 Release) Publication GitHub Bioconductor PCxN website

Pathprint

GitHub Bioconductor Publication

Winston Hide

he/him
Winston Hide, PhD, is a computational biologist specializing in bioinformatics, genomics, and systems biology. He is an Associate Professor of Pathology at Harvard Medical School and Director of the RNA Precision Medicine Core at BIDMC. His research focuses on molecular resilience in neurodegenerative diseases, using multi-omic data to identify therapeutic targets. He founded the South African National Bioinformatics Institute, advancing bioinformatics training and capacity in Africa. His current work integrates spatial transcriptomics and AI to drive precision medicine for neurodegenerative diseases.

About

The goal of the Hide laboratory is to impact human health through understanding and translation of the underlying mechanisms of diseases. With the aim of providing effective therapies, our group works on discovery of genes, pathways and processes that drive disease development. We work assuming...

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.

Prokopenko, Dmitry, Sanghun Lee, Julian Hecker, Kristina Mullin, Sarah Morgan, Yuriko Katsumata, Alzheimer’s Disease Neuroimaging Initiative, et al. 2022. “Region-Based Analysis of Rare Genomic Variants in Whole-Genome Sequencing Datasets Reveal Two Novel Alzheimer’s Disease-Associated Genes: DTNB and DLG2.”. Molecular Psychiatry 27 (4): 1963-69.