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Human Genetics: Discovering Novel Therapeutic Targets for Parkinson's Disease, Bruno A. Benitez, MD
Benitez, Bruno A. 2024. Human Genetics: Discovering Novel Therapeutic Targets for Parkinson’s Disease, Bruno A. Benitez, MD.
Nuclei Isolation from human cortical tissue for enrichment of endothelial and microglial cells
Benitez, Bruno A. 2024. “Nuclei Isolation from Human Cortical Tissue for Enrichment of Endothelial and Microglial Cells”. Protocols.Io.
Transcriptomic analyses of human brains with Alzheimer’s disease identified dysregulated epilepsy-causing genes
Eteleeb, Abdallah M, Suelen Santos Alves, Stephanie Buss, Mouhsin M Shafi, Daniel Z Press, Norberto Garcia-Cairasco, and Bruno A. Benitez. Submitted. “Transcriptomic Analyses of Human Brains With Alzheimer’s Disease Identified Dysregulated Epilepsy-Causing Genes.”
Uncovering the molecular mechanisms behind Alzheimer’s and Parkinson’s disease through multi-omics: an interview with Bruno A. Benitez
Benitez, Bruno A. 2025. “Uncovering the Molecular Mechanisms Behind Alzheimer’s and Parkinson’s Disease through Multi-Omics: An Interview With Bruno A. Benitez”. BioTechniques.
Ifeoma Mba-Madubuike
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Lab Alumni
Niko Nikanen Zhaohua Wang Divya Palanisamy Amelia Li
Multi-Omics Approaches Applied to Neurodegenerative Diseases
One of the research interests in our lab is focused on the deep-molecular characterization of a clinically well-defined cohort of patients anchored in genomic data. Alzheimer’s (AD) and Parkinson’s disease (PD) are heterogeneous disorders with identifiable clinical-pathological subtypes based on...
Cellular Atlas of Parkinson's Disease
Detailed molecular characterization of cell-specific transcriptomic states throughout multiple brain regions beyond nigrostriatal dopaminergic degeneration will provide mechanistic insights into both motor and non-motor PD symptoms. We will integrate neuropathology and snRNA-Seq data to identify a...