IL-17A and IL-17F in tissue homeostasis, inflammation and regeneration.
Adamopoulos, Iannis E, and Vijay Kuchroo. 2023. “IL-17A and IL-17F in Tissue Homeostasis, Inflammation and Regeneration.”. Nature Reviews. Rheumatology 19 (9): 535-36.
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Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes.
Merleev, Alexander A, Stephanie T Le, Claire Alexanian, Atrin Toussi, Yixuan Xie, Alina I Marusina, Steven M Watkins, et al. 2022. “Biogeographic and Disease-Specific Alterations in Epidermal Lipid Composition and Single-Cell Analysis of Acral Keratinocytes.”. JCI Insight 7 (16).
Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G.
Merleev, Alexander, Antonio Ji-Xu, Atrin Toussi, Lam C Tsoi, Stephanie T Le, Guillaume Luxardi, Xianying Xing, et al. 2022. “Proprotein Convertase Subtilisin/Kexin Type 9 Is a Psoriasis-Susceptibility Locus That Is Negatively Related to IL36G.”. JCI Insight 7 (16).
Adamopoulos Lab
Arthritis, Osteoclasts, Psoriasis, Autoimmunity, Bone biology, Dr. Iannis Adamopoulos, Adamopoulos Lab
IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation.
Li, Hao, Maria G Tsokos, Rhea Bhargava, Iannis E Adamopoulos, Hanni Menn-Josephy, Isaac E Stillman, Philip Rosenstiel, Jarrat Jordan, and George C Tsokos. 2021. “IL-23 Reshapes Kidney Resident Cell Metabolism and Promotes Local Kidney Inflammation.”. The Journal of Clinical Investigation 131 (12).
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky, Daniel J, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, et al. 2021. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition)1.”. Autophagy 17 (1): 1-382.
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Research Overview Bone Biology Bone destruction commonly occurs in multiple rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis and lupus. In our laboratory, we study the molecular mechanisms that control osteoclast differentiation and activation, the cells that are primarily...
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IL-27 attenuates IL-23 mediated inflammatory arthritis.
Sarin, Ritu, Ran Gu, Zahra Jalali, Emanual Maverakis, Maria G Tsokos, and Iannis E Adamopoulos. 2023. “IL-27 Attenuates IL-23 Mediated Inflammatory Arthritis.”. Clinical Immunology (Orlando, Fla.) 251: 109327.
Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.
Marusina, Alina I, Antonio Ji-Xu, Stephanie T Le, Atrin Toussi, Lam C Tsoi, Qinyuan Li, Guillaume Luxardi, et al. 2023. “Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.”. The Journal of Investigative Dermatology 143 (7): 1157-1167.e10.