T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy
Sharabi, A., and G. C. Tsokos. 2020. “T Cell Metabolism: New Insights in Systemic Lupus Erythematosus Pathogenesis and Therapy”. Nat Rev Rheumatol 16: 100-112.
Search
Search results
124 results found
Cell derived extracellular matrix-rich biomimetic substrate supports podocyte proliferation, differentiation and maintenance of native phenotype
Satyam, A., M. G. Tsokos, J. S. Tresback, D. I. Zeugolis, and G. C. Tsokos. 2020. “Cell Derived Extracellular Matrix-Rich Biomimetic Substrate Supports Podocyte Proliferation, Differentiation and Maintenance of Native Phenotype”. Adv Funct Mater 30.
Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity
Psarras, A., A. Alase, A. Antanaviciute, I. M. Carr, M. Y. Md Yusof, M. Wittmann, P. Emery, G. C. Tsokos, and E. M. Vital. 2020. “Functionally Impaired Plasmacytoid Dendritic Cells and Non-Haematopoietic Sources of Type I Interferon Characterize Human Autoimmunity”. Nat Commun 11: 6149.
Metabolic control of T cells in autoimmunity
Kono, M., N. Yoshida, and G. C. Tsokos. 2020. “Metabolic Control of T Cells in Autoimmunity”. Curr Opin Rheumatol 32: 192-99.
Current Insights and Future Prospects for Targeting IL-17 to Treat Patients With Systemic Lupus Erythematosus
Koga, T., K. Ichinose, A. Kawakami, and G. C. Tsokos. 2020. “Current Insights and Future Prospects for Targeting IL-17 to Treat Patients With Systemic Lupus Erythematosus”. Front Immunol 11: 624971.
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.
Xu, Meng, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P Hoefig, Christine Hohn, et al. 2024. “The Thymocyte-Specific RNA-Binding Protein Arpp21 Provides TCR Repertoire Diversity by Binding to the 3’-UTR and Promoting Rag1 MRNA Expression.”. Nature Communications 15 (1): 2194.
The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity.
Pan, Wenliang, Maria G Tsokos, Marc Scherlinger, Wei Li, and George C Tsokos. 2024. “The PP2A Regulatory Subunit PPP2R2A Controls NAD+ Biosynthesis to Regulate T cell Subset Differentiation in Systemic Autoimmunity.”. Cell Reports 43 (7): 114379.
The emergence of SLE-causing UNC93B1 variants in 2024.
Tsokos, George C. 2024. “The Emergence of SLE-Causing UNC93B1 Variants in 2024.”. Nature Reviews. Rheumatology.
Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.
Rubio, Jose, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O’Connell, George C Tsokos, and Vasileios Kyttaris. 2024. “Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.”. ACR Open Rheumatology.
Aberrant T follicular helper cells generated by TH17 cell plasticity in the gut promote extraintestinal autoimmunity.
Fan, Tingting, Chi Tai, Kiah C Sleiman, Madeline P Cutcliffe, Haram Kim, Ye Liu, Jianying Li, et al. 2025. “Aberrant T Follicular Helper Cells Generated by TH17 Cell Plasticity in the Gut Promote Extraintestinal Autoimmunity.”. Nature Immunology 26 (5): 790-804.