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139 results found

The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.

Publication: Journal Article

Xu, Meng, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P Hoefig, Christine Hohn, et al. 2024. “The Thymocyte-Specific RNA-Binding Protein Arpp21 Provides TCR Repertoire Diversity by Binding to the 3’-UTR and Promoting Rag1 MRNA Expression.”. Nature Communications 15 (1): 2194.

The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity.

Publication: Journal Article

Pan, Wenliang, Maria G Tsokos, Marc Scherlinger, Wei Li, and George C Tsokos. 2024. “The PP2A Regulatory Subunit PPP2R2A Controls NAD+ Biosynthesis to Regulate T cell Subset Differentiation in Systemic Autoimmunity.”. Cell Reports 43 (7): 114379.

Wenliang Pan, PhD

Person: Instructor in Medicine

I obtained a PhD degree from the Chinese University of Hong Kong (CUHK) in Biomedical Sciences, Hong Kong. After that I join Tsokos lab for postdoctoral training. My current project are extensively involved in the study of the role of PP2A in the regulation of immune cell function including its role...

The emergence of SLE-causing UNC93B1 variants in 2024.

Publication: Journal Article

Tsokos, George C. 2024. “The Emergence of SLE-Causing UNC93B1 Variants in 2024.”. Nature Reviews. Rheumatology.

Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.

Publication: Journal Article

Rubio, Jose, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O’Connell, George C Tsokos, and Vasileios Kyttaris. 2024. “Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.”. ACR Open Rheumatology.

Curb complement to cure COVID-19

Publication: Journal Article

Satyam, A., and G. C. Tsokos. 2020. “Curb Complement to Cure COVID-19”. Clin Immunol 221: 108603.

TCR-alpha/beta CD4(-) CD8(-) double negative T cells arise from CD8(+) T cells

Publication: Journal Article

Rodriguez-Rodriguez, N., G. Flores-Mendoza, S. A. Apostolidis, F. Rosetti, G. C. Tsokos, and J. C. Crispin. 2020. “TCR-Alpha/Beta CD4(-) CD8(-) Double Negative T Cells Arise from CD8(+) T Cells”. J Leukoc Biol 108: 851-57.

Retraction Note: Microglia-dependent synapse loss in type I interferon-mediated lupus

Publication: Journal Article

Bialas, A. R., J. Presumey, A. Das, C. E. van der Poel, P. H. Lapchak, L. Mesin, G. Victora, et al. 2020. “Retraction Note: Microglia-Dependent Synapse Loss in Type I Interferon-Mediated Lupus”. Nature 578: 177.

Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes

Publication: Journal Article

Jung, S., M. Ben Nasr, B. Bahmani, V. Usuelli, J. Zhao, G. Sabiu, A. J. Seelam, et al. 2023. “Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes”. Adv Mater 35: e2300812.

Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus

Publication: Journal Article

Morita, M., M. Mizui, S. Masuyama, G. C. Tsokos, and Y. Isaka. 2022. “Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus”. Front Immunol 13: 855812.