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Overview of HDDC Cores and Services Use the links for detailed descriptions, locations and contact information. Biomedical CORE B: Microscopy and Histopathology Histology(paraffin and frozen sections) Electron and Confocal Microscopy Photodocumentation and Widefield Microscopy Advanced Imaging...

Core Technician: Sierra Anderson Services Polarized epithelial cell lines maintained and available: human intestinal T84, HT29, Caco2-BBe, and SKCO-15; canine renal MDCK I and MDCK II cells; porcine kidney LL-CPK cells Second site storage available for specialized cell lines prepared by HDDC members...

Criteria for Membership in the HDDC Full Members Full Members are independently funded by NIH R-series, K-series, PO1, UO1, or equivalent government, foundation, or industry grants. (This criterion is established by the NIDDK.) Associate Members Associate Members do not currently have independently...

Core Scientist: Naresh Singh Redhu, PhD Analytical Flow Cytometry and Cell Sorting High-end analytical flow cytometry is available for simultaneous measurement of protein expression and other characteristics of epithelial and other cell types. This includes: i) Analysis of cell surface or...

There are 3 locations for Core B services: There are 3 Longwood-area locations for Core B services and 2 Harvard-based locations for access to advanced imaging instrumentation and services: For information about the integrated services provided in Core B, please contact Susan Hagen, PhD, Core B...

Benefits of Membership in the HDDC Inclusion in all HDDC activities All members receive advance notice of HDDC seminars, symposia and special events. Reduced fees for use of Core servicesFull Members, Associate Members and Clinical Associates should discuss subsidies with the core director since...

Core Scientists: David Breault, MD, PhD, Amy O’Connell, MD, PhD Core Technicians: Eric Stas, MS, Wanshu Qi, PhD, Prabhath Mannam Services This service provides in-depth protocols, hands-on training, biologics, and ongoing support for the derivation and culture of gastrointestinal organoids/enteroids...

The mission of the Center’s CTRP is to support basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. To forge connections and support collaboration between HDDC Clinical Associates and Members To...

How to Join the HDDC If you are interested in joining the HDDC, please begin by contacting HDDC Director Dr. Wayne Lencer or any member of the Executive Committee to discuss eligibility. Applicants then submit a letter to the Dr. Wayne Lencer detailing the relevance of their current research to one...

Core Scientist: Wayne Lencer, MD Services Access to instrumentation for transepithelial electrophysiology and flux studies (Ussing chambers and voltage clamp modified for tissue and cell culture and interfaced to computer controlled voltage clamp and digital analysis) is available to membership as...