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Membership Criteria

Criteria for Membership in the HDDC Full Members Full Members are independently funded by NIH R-series, K-series, PO1, UO1, or equivalent government, foundation, or industry grants. (This criterion is established by the NIDDK.) Associate Members Associate Members do not currently have independently...

Flow Cytometry and Cell Sorting

Core Scientist: Naresh Singh Redhu, PhD Analytical Flow Cytometry and Cell Sorting High-end analytical flow cytometry is available for simultaneous measurement of protein expression and other characteristics of epithelial and other cell types. This includes: i) Analysis of cell surface or...

Core Services

Overview of HDDC Cores and Services Use the links for detailed descriptions, locations and contact information. Biomedical CORE B: Microscopy and Histopathology Histology(paraffin and frozen sections) Electron and Confocal Microscopy Photodocumentation and Widefield Microscopy Advanced Imaging...

Polarized Epithelial Cell Culture

Core Technician: Sierra Anderson Services Polarized epithelial cell lines maintained and available: human intestinal T84, HT29, Caco2-BBe, and SKCO-15; canine renal MDCK I and MDCK II cells; porcine kidney LL-CPK cells Second site storage available for specialized cell lines prepared by HDDC members...

Epithelial Cell and Mucosal Immunology

Epithelial Cell and Mucosal Immunology Core provides the infrastructure, biologic resources, expertise, and training for innovative and cross-disciplinary research on epithelial biology and immune function in mucosal surfaces and solid organs of the GI tract. Core Director: Wayne Lencer, MD Contact...

Clinical and Translational Research

HDDC Clinical and Translational Research Allegretti, Jessica, MD BWH Banks, Peter, MD BWH Bousvaros, Athos, MD, MPH BCH Crowley, Paul (McGreggor), MD BCH DeMaso, Dave, MD BCH Duggan, Christopher, MD, MPH BCH Duncan, Pete, MD, MPH BCH Feldman, Henry, PhD BCH Grand, Richard, MD (emeritis) BCH...

Clinical Translational Research Program

Overview: The Clinical and Translational Research Program (a Clinical Component of the Administrative Core of the HDDC). The services offered by the CTRP promote translation of basic research advances into improved clinical care by offering fresh and archived human specimens, associated clinical...

Microscopy and Histopathology

There are 3 locations for Core B services: There are 3 Longwood-area locations for Core B services and 2 Harvard-based locations for access to advanced imaging instrumentation and services: For information about the integrated services provided in Core B, please contact Susan Hagen, PhD, Core B...

Member Benefits

Benefits of Membership in the HDDC Inclusion in all HDDC activities All members receive advance notice of HDDC seminars, symposia and special events. Reduced fees for use of Core servicesFull Members, Associate Members and Clinical Associates should discuss subsidies with the core director since...

Gastrointestinal Organoid Derivation and Culture

Core Scientists: David Breault, MD, PhD, Amy O’Connell, MD, PhD Core Technicians: Eric Stas, MS, Wanshu Qi, PhD, Prabhath Mannam Services This service provides in-depth protocols, hands-on training, biologics, and ongoing support for the derivation and culture of gastrointestinal organoids/enteroids...