We say farewell to Sumedha
We say farewell to Sumedha today! Best of luck with your future endeavors!
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Recent advances in the development of RIPK2 modulators for the treatment of inflammatory diseases.
Pham, Anh-Tuan, Amanda Franceschini Ghilardi, and Lijun Sun. 2023. “Recent Advances in the Development of RIPK2 Modulators for the Treatment of Inflammatory Diseases.”. Frontiers in Pharmacology 14: 1127722.
In silico discovery and therapeutic potential of IDO1 and TDO2 inhibitors.
Jernigan, Finith E, and Lijun Sun. 2017. “In Silico Discovery and Therapeutic Potential of IDO1 and TDO2 Inhibitors.”. Future Medicinal Chemistry 9 (12): 1309-11.
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Solomon finished his internship at our lab!
Solomon completed his summer internship at our lab. Over the last three months, he has proved that he is an outstanding young scientist. We greatly appreciate Solomon's contribution to our drug discovery effort and wish him the best of luck in his future endeavors.
New publication on European Journal of Medicinal Chemistry
Check out our new paper on European Journal of Medicinal Chemistry. In this work, we describe the "Discovery of selective Orai channel blockers bearing an indazole or a pyrazole scaffold". Congratulations to all the authors! Link to our paper: https://www.sciencedirect.com/science/article/pii...
Insights Derived from the Synthesis of a Complex Core 2 Glycan.
Dhakal, Bibek, Appi Mandhapati, Simon Park, Lijun Sun, and Elliot L Chaikof. 2024. “Insights Derived from the Synthesis of a Complex Core 2 Glycan.”. The Journal of Organic Chemistry 89 (16): 11641-58.
Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase.
Koerner, Steffi K, Jun-Ichi Hanai, Sha Bai, Finith E Jernigan, Miwa Oki, Chieko Komaba, Emi Shuto, Vikas P Sukhatme, and Lijun Sun. 2017. “Design and Synthesis of Emodin Derivatives As Novel Inhibitors of ATP-Citrate Lyase.”. European Journal of Medicinal Chemistry 126: 920-28.
Novel indolyl-chalcones target stathmin to induce cancer cell death.
Wegiel, Barbara, Yiqiang Wang, Mailin Li, Finith Jernigan, and Lijun Sun. 2016. “Novel Indolyl-Chalcones Target Stathmin to Induce Cancer Cell Death.”. Cell Cycle (Georgetown, Tex.) 15 (9): 1288-94.
Synthesis, crystallographic characterization and electrochemical property of a copper(II) complex of the anticancer agent elesclomol.
Vo, Nha Huu, Zhiqiang Xia, Jason Hanko, Tong Yun, Steve Bloom, Jianhua Shen, Keizo Koya, Lijun Sun, and Shoujun Chen. 2014. “Synthesis, Crystallographic Characterization and Electrochemical Property of a Copper(II) Complex of the Anticancer Agent Elesclomol.”. Journal of Inorganic Biochemistry 130: 69-73.