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Go to CalR, a web application for indirect calorimetry analysis. The CalR project: There is a critical lack of standardization for indirect calorimetry experiments to measure body composition ( Corrigan et al eLife 2020, Banks et al Nature Metabolism 2025). Currently, the same dataset can produce...

Energy Balance Metabolic Core at BIDMC and Harvard Medical School is a facility designed for the measurement of energy intake, nutritional status, and energy expenditure in experimental mice. CalR Equipment & Technologies Example Experiments

Thermogenesis: cold temperature challenge Thermogenesis: beta-adrenergic agonist activation of mice housed at thermoneutral temperatures Pharmacologic induction of metabolic rate (T3) Diet-induced obesity Optogenetic stimulation of food intake Chemogenetic stimulation of metabolism Induction of...

For any inquiries, please feel free to contact us at: EnergyBalanceCore@bidmc.harvard.edu

Beth Israel Deaconess Medical Center and Harvard Medical School - The home of CalR Energy Balance Metabolic Core at BIDMC and Harvard Medical School is a facility designed for the measurement of energy intake, nutritional status, and energy expenditure in experimental mice. This facility consists of...

Our facilities were updated and re-launched as an institutional Energy Balance Metabolic Core in 2019 to continue the tradition of excellence in metabolic research. This included a bomb calorimeter and a thermal imaging camera. In 2020 we obtained a Promethion indirect calorimeter and DSI’s...