Search

Beth Israel Deaconess Medical Center and Harvard Medical School - The home of CalR Energy Balance Metabolic Core at BIDMC and Harvard Medical School is a facility designed for the measurement of energy intake, nutritional status, and energy expenditure in experimental mice. This facility consists of...

Our facilities were updated and re-launched as an institutional Energy Balance Metabolic Core in 2019 to continue the tradition of excellence in metabolic research. This included a bomb calorimeter and a thermal imaging camera. In 2020 we obtained a Promethion indirect calorimeter and DSI’s...

​ Male C57Bl/6J mice housed at thermoneutrality were administered the β-adrenergic agonist CL 316,243, and changes in oxygen consumption were continuously measured.

C57Bl/6J female mice were monitored for body temperature and metabolic rate during the dark photoperiod without food, with the blue trace representing a fed mouse and the red trace a fasted mouse exhibiting torpor (Hrvatin et al., Nature, 2020).

In vivo stable isotope tracing with U-¹³C₆ D-mannitol and U-¹³C₆ D-glucose was conducted to enable ¹³CO₂ monitoring in the Promethion indirect calorimeter, with data plotted using CalR for conventional (blue) and commensal-depleted (red) mice (Vieira et al., in press).