A neutralizing APOA5 monoclonal antibody reduces amounts of lipoprotein lipase in capillaries and triggers hypertriglyceridemia.
Yang, Ye, Anne P Beigneux, Troy L Lowe, Yan Q Chen, Katherine Xie, Hyesoo Jung, Yiping Tu, et al. 2026. “A Neutralizing APOA5 Monoclonal Antibody Reduces Amounts of Lipoprotein Lipase in Capillaries and Triggers Hypertriglyceridemia.”. Proceedings of the National Academy of Sciences of the United States of America 123 (1): e2528664123.