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Pyruvate Dehydrogenase Activity Is Decreased in the Peripheral Blood Mononuclear Cells of Patients with Sepsis. A Prospective Observational Trial.

Nuzzo, Erin, Katherine M Berg, Lars W Andersen, Julia Balkema, Sophia Montissol, Michael N Cocchi, Xiaowen Liu, and Michael W Donnino. 2015. “Pyruvate Dehydrogenase Activity Is Decreased in the Peripheral Blood Mononuclear Cells of Patients With Sepsis. A Prospective Observational Trial.”. Annals of the American Thoracic Society 12 (11): 1662-6.

About Us

The Biomarker and Metabolism Research Core is the research laboratory arm of the Center for Resuscitation Science. This Lab, under the direction of Dr. Xiaowen Liu, provides crucial information to the clinical team concerning the cellular respiration and biomarkers of our patients enrolled in the...

Real Time Metabolism Assays

Seahorse XFe 96 Flux Analyzer Seahorse Overview The Seahorse XFe96 Extracellular Flux Analyzer simultaneously measures Oxygen Consumption Rate (OCR) and Extracellular Acidification Rate (ECAR) of live cells in a 96-well plate format in order to interrogate changes in oxidative phosphorylation and...