Search

Search results

11 results found

Distinct fibroblast subsets drive inflammation and damage in arthritis

Publication: Journal Article

Croft, AP, Campos, Jansen, JD Turner, Marshall, Attar, Savary, et al. 2019. “Distinct Fibroblast Subsets Drive Inflammation and Damage in Arthritis”. Nature 570: 246-51.

Instructors

Page

IMPACT: Genomic annotation of cell-state-specific regulatory elements inferred from the epigenome of bound transcription factors

Publication: Journal Article

Amariuta, Tiffany, Yang Luo, Steven Gazal, Emma Elisabeth Davenport, Bryce Geijn, Kazuyoshi Ishigaki, Harm-Jan Westra, et al. 2019. “IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors”. The American Journal of Human Genetics 104 (5): 879-95.

Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms

Publication: Journal Article

Fine, Rebecca, Tune Pers, Tiffany Amariuta, Soumya Raychaudhuri, and Joel Hirschhorn. 2019. “Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms”. American Journal of Human Genetics 104 (6): 1025-39.

Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians

Publication: Journal Article

Luo, Suliman, Asgari, Amariuta, Baglaenko, Martinez-Bonet, Ishigaki, et al. 2019. “Early Progression to Active Tuberculosis Is a Highly Heritable Trait Driven by 3q23 in Peruvians”. Nature Communications 10 (3765).

Kamil Slowikowski graduates from Harvard and joins Massachusetts General Hospital

News: August 13, 2019

Kamil and Soumya, Countway Library of Medicine, Boston, MA. 2019. Examination Chairman: Peter Kharchenko Examiners: Chirag Patel, I-Cheng Ho, and Jeffrey Browning Kamil graduated from the Bioinformatics and Integrative Genomics PhD program at Harvard University in Boston, MA. His dissertation was...

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

Publication: Journal Article

Der, Suryawanshi, Morozov, Kustagi, Goilav, Ranabathou, Izmirly, et al. 2019. “Tubular Cell and Keratinocyte Single-Cell Transcriptomics Applied to Lupus Nephritis Reveal Type I IFN and Fibrosis Relevant Pathways”. Nature Immunology 20 (7): 915-27.

Joyce Kang

Person: Harvard Medical School MD-PhD Student

I’m an MD/PhD student (MD though the Harvard/MIT HST program and PhD in Bioinformatics & Integrative Genomics). I joined the Raychaudhuri Lab in the summer of 2019 and am currently working on developing computational methods to efficiently map single-cell RNA-seq datasets against multi-million-cell...

Macrophages tailor their function according to the signals found in tissue microenvironments, assuming a wide spectrum of phenotypes. A detailed understanding of macrophage phenotypes in human tissues is limited. Using single-cell RNA sequencing, we defin

Publication: Journal Article

Kuo, Ding, IS Cohn, Zhang, Wei, DA Rao, Rozo, et al. 2019. “Macrophages Tailor Their Function According to the Signals Found in Tissue Microenvironments, Assuming a Wide Spectrum of Phenotypes. A Detailed Understanding of Macrophage Phenotypes in Human Tissues Is Limited. Using Single-Cell RNA Sequencing, We Defin”. Science Translational Medicine 11 (491): eaau8587.

Defining Inflammatory Cell States in Rheumatoid Arthritis Joint Synovial Tissues by Integrating Single-cell Transcriptomics and Mass Cytometry

Publication: Journal Article

Zhang, F.#, Wei, Slowikowski, CY# Fonseka, DA# Rao, Kelly, SM Goodman, et al. 2019. “Defining Inflammatory Cell States in Rheumatoid Arthritis Joint Synovial Tissues by Integrating Single-Cell Transcriptomics and Mass Cytometry”. Nature Immunology 20: 928-42.