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Yakir Reshef

Person: Medical Resident

I am an MD/PhD computer scientist currently training in internal medicine at Brigham and Women's Hospital. I joined the Raychaudhuri lab in 2019 and have been working on developing new methods for comparing single-cell data from multiple conditions. In 2018, I completed a PhD in computer science at...

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Publication: Journal Article

Gutierrez-Arcelus, Maria#, Yuriy# Baglaenko, Jatin Arora, Susan Hannes, Yang Luo, Tiffany Amariuta, Nikola Teslovich, et al. 2020. “Allele-Specific Expression Changes Dynamically During T Cell Activation in HLA and Other Autoimmune Loci”. Nature Genetics 52: 247-53.

Formate assay in body fluids: application in methanol poisoning

Publication: Journal Article

Makar, McMartin, Palese, and Tephly. 1975. “Formate Assay in Body Fluids: Application in Methanol Poisoning”. Biochem Med 13 (2): 117-26.

Delineation of the intimate details of the backbone conformation of pyridine nucleotide coenzymes in aqueous solution

Publication: Journal Article

Bose, and Sarma. 1975. “Delineation of the Intimate Details of the Backbone Conformation of Pyridine Nucleotide Coenzymes in Aqueous Solution”. Biochem Biophys Res Commun 66 (4): 1173-9.

Pleural effusion associated with aortitis syndrome

Publication: Journal Article

Kawai, Yamada, Tsuneda, Aoyagi, and Mikata. 1975. “Pleural Effusion Associated With Aortitis Syndrome”. Chest 68 (6): 826-8.

RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares

Publication: Journal Article

Orange, Dana E., Vicky Yao, Kirsty Sawicka, John Fak, Mayu O. Frank, Salina Parveen, Nathalie E. Blachere, et al. 2020. “RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares”. New England Journal of Medicine 383 (3): 218-28.

Disruptive innovation in rheumatology: new networks of global public–private partnerships are needed to take advantage of scientific progress

Publication: Journal Article

Huizinga, Tom, Michael Holers, Jennifer Anolik, Michael Brenner, Christopher Dominic Buckley, Vivian Bykerk, Sean Connolly, et al. 2020. “Disruptive Innovation in Rheumatology: New Networks of Global Public–private Partnerships Are Needed to Take Advantage of Scientific Progress”. Annals of the Rheumatic Diseases 79 (5): 553-55.

HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors

Publication: Journal Article

Ishigaki, Lagattuta, Luo, James, Buckner, and Raychaudhuri. 2020. “HLA Autoimmune Risk Alleles Restrict the Hypervariable Region of T Cell Receptors.”

Fast, sensitive and accurate integration of single-cell data with Harmony

Publication: Journal Article

Korsunsky, Ilya, Nghia Millard, Jean Fan, Kamil Slowikowski, Fan Zhang, Kevin Wei, Yuriy Baglaenko, Michael Brenner, Po-Ru Loh, and Soumya Raychaudhuri. 2019. “Fast, Sensitive and Accurate Integration of Single-Cell Data With Harmony”. Nat Methods 16 (12): 1289-96.

Genes with High Network Connectivity Are Enriched for Disease Heritability

Publication: Journal Article

Kim, Samuel, Chengzhen Dai, Farhad Hormozdiari, Bryce Geijn, Steven Gazal, Yongjin Park, Luke O’Connor, et al. 2019. “Genes With High Network Connectivity Are Enriched for Disease Heritability”. Am J Hum Genet 105 (6): 1302.