Stepping to infinity along Gaussian primes
Loh, Po-Ru. 2007. “Stepping to Infinity Along Gaussian Primes”. American Mathematical Monthly 114 (2): 142–151.
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Multiethnic polygenic risk scores improve risk prediction in diverse populations
Márquez-Luna, Carla, Po-Ru Loh, and Alkes Price. 2017. “Multiethnic Polygenic Risk Scores Improve Risk Prediction in Diverse Populations”. Genet Epidemiol 41 (8): 811-23.
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection
Schoech, Armin, Daniel Jordan, Po-Ru Loh, Steven Gazal, Luke O’Connor, Daniel Balick, Pier Palamara, Hilary Finucane, Shamil R. Sunyaev, and Alkes Price. 2019. “Quantification of Frequency-Dependent Genetic Architectures in 25 UK Biobank Traits Reveals Action of Negative Selection”. Nat Commun 10 (1): 790.
Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes
Chung, Wonil, Jun Chen, Constance Turman, Sara Lindström, Zhaozhong Zhu, Po-Ru Loh, Peter Kraft, and Liming Liang. 2019. “Efficient Cross-Trait Penalized Regression Increases Prediction Accuracy in Large Cohorts Using Secondary Phenotypes”. Nat Commun 10 (1): 569.
Estimating cross-population genetic correlations of causal effect sizes
Galinsky, Kevin, Yakir A Reshef, Hilary Finucane, Po-Ru Loh, Noah Zaitlen, Nick Patterson, Brielin Brown, and Alkes Price. 2019. “Estimating Cross-Population Genetic Correlations of Causal Effect Sizes”. Genet Epidemiol 43 (2): 180-88.
Fast, sensitive and accurate integration of single-cell data with Harmony
Korsunsky, Ilya, Nghia Millard, Jean Fan, Kamil Slowikowski, Fan Zhang, Kevin Wei, Yuriy Baglaenko, Michael Brenner, Po-Ru Loh, and Soumya Raychaudhuri. 2019. “Fast, Sensitive and Accurate Integration of Single-Cell Data With Harmony”. Nat Methods 16 (12): 1289-96.
GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health
Zhao, Yajie, Stasa Stankovic, Mine Koprulu, Eleanor Wheeler, Felix Day, Hana Lango Allen, Nicola Kerrison, et al. 2021. “GIGYF1 Loss of Function Is Associated With Clonal Mosaicism and Adverse Metabolic Health”. Nat Commun 12 (1): 4178.
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection
Zekavat, Seyedeh, Shu-Hong Lin, Alexander Bick, Aoxing Liu, Kaavya Paruchuri, Chen Wang, Md Mesbah Uddin, et al. 2021. “Hematopoietic Mosaic Chromosomal Alterations Increase the Risk for Diverse Types of Infection”. Nat Med 27 (6): 1012-24.
Chromosomal alterations among age-related haematopoietic clones in Japan
Terao, Chikashi, Akari Suzuki, Yukihide Momozawa, Masato Akiyama, Kazuyoshi Ishigaki, Kazuhiko Yamamoto, Koichi Matsuda, et al. 2020. “Chromosomal Alterations Among Age-Related Haematopoietic Clones in Japan”. Nature 584 (7819): 130-35.
Influences of rare copy-number variation on human complex traits
Hujoel, Margaux LA, Maxwell Sherman, Alison Barton, Ronen Mukamel, Vijay Sankaran, Chikashi Terao, and Po-Ru Loh. 2022. “Influences of Rare Copy-Number Variation on Human Complex Traits”. Cell 185 (22): 4233-4248.e27.