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Obesity and type 2 diabetes (T2D) are leading global health threats. Innovative multi-pronged approaches are needed to combat both epidemics. Many risk factors for obesity and T2D – beyond genetics – are present before birth, reflecting the influence of environmental factors on germ cells and on the...

Are you a recent college graduate with interest in an exciting project investigating epigenetic mechanisms underlying diabetes? If so, we have a research assistant position ready for you in the Patti Lab! We have a long track record of helping individuals to achieve their goals for acceptance in...

In studies in collaboration with the Tseng Lab, and with the generous support of the Chan-Zuckerberg Initiative (Seed Networks, component of the Human Cell Atlas), we are utilizing single-nucleus RNA sequencing and ATAC-sequencing to identify subpopulations of adipose tissue resident cells and their...

Please see "news" tab! For all Patti Lab publications, please click on this link: Patti ME[Author] - Search Results - PubMed (nih.gov)

Congratulations to our collaborative team on the publication of our paper in Nature Metabolism in April 2025 ! In this paper (Pubmed, PMID 40186075) we demonstrate that individuals with post-bariatric hypoglycemia have differences in bile acid metabolism. To detect this we measured bile acids in...