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Obesity and type 2 diabetes (T2D) are leading global health threats. Innovative multi-pronged approaches are needed to combat both epidemics. Many risk factors for obesity and T2D – beyond genetics – are present before birth, reflecting the influence of environmental factors on germ cells and on the...

Are you a recent college graduate with interest in an exciting project investigating epigenetic mechanisms underlying diabetes? If so, we have a research assistant position ready for you in the Patti Lab! We have a long track record of helping individuals to achieve their goals for acceptance in...

In studies in collaboration with the Tseng Lab, and with the generous support of the Chan-Zuckerberg Initiative (Seed Networks, component of the Human Cell Atlas), we are utilizing single-nucleus RNA sequencing and ATAC-sequencing to identify subpopulations of adipose tissue resident cells and their...

Please see "news" tab! For all Patti Lab publications, please click on this link: Patti ME[Author] - Search Results - PubMed (nih.gov)

We recently identified GDF15 as a hormone released in response to hypoglycemia, which may contribute to symptoms experienced during hypoglycemia. This paper was published in Cell Reports Medicine in March 2026 (Pubmed, PMID 41806840). Congratulations to first author Rafael Ferraz-Bannitz PhD and the...