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Age-dependent effect of hearing loss on cortical inhibitory synapse function.

Publication: Journal Article

AE, Takesian, Kotak VC, and Sanes DH. 2012. “Age-Dependent Effect of Hearing Loss on Cortical Inhibitory Synapse Function.”. J Neurophysiol 107 (3): 937-47.

News & Events

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Takesian Lab Opened in November 2017! Ana Castro and Emma He joined the laboratory after giving a fantastic presention at ARO in San Diego! An Early Career Award by NIDCD (March 2018) will fund an exciting project on an unexpected long-range projection from auditory cortex. Vivek Kanumuri, M.D., a...

Balancing plasticity/stability across brain development

Publication: Journal Article

AE, Takesian, and Hensch TK. 2013. “Balancing Plasticity/Stability across Brain Development”. Prog Brain Res 207: 3-34.

Hearing loss prevents the maturation of GABAergic transmission in the auditory cortex

Publication: Journal Article

VC, Kotak, Takesian AE, and Sanes DH. 2008. “Hearing Loss Prevents the Maturation of GABAergic Transmission in the Auditory Cortex”. Cereb Cortex 18 (9): 2098-108.

Sensory integration in mouse insular cortex reflects GABA circuit maturation

Publication: Journal Article

N, Gogolla, Takesian AE, Feng G, Fagiolini M, and Hensch TK. 2014. “Sensory Integration in Mouse Insular Cortex Reflects GABA Circuit Maturation”. Neuron 83 (4).

Hearing loss differentially affects thalamic drive to two cortical interneuron subtypes

Publication: Journal Article

AE, Takesian, Kotak VC, Sharma N, and Sanes DH. 2013. “Hearing Loss Differentially Affects Thalamic Drive to Two Cortical Interneuron Subtypes”. J Neurophysiol 110 (4): 999-1008.

Ana Castro

Person: Boston University, Masters in Public Health (M.P.H.) Candidate

Development and experience-dependent development of thalamic inputs to layer 1 cortical interneurons

Research

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The developing brain dramatically rewires in response to the external world during early ‘critical periods’, but this capacity diminishes with adulthood. A clear advantage of time-limited critical periods is that the developing brain circuits are assembled to represent the relevant aspects of our...

Resources

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Please contact Dr. Anne Takesian ( anne_takesian@meei.harvard.edu) for information about lab resources. Future custom programs and data will be made available here.

Circuitry and Plasticity of Auditory Cortex

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Our unique perception of the acoustic world evolves with experience throughout our lifespan. As neuroscientists we believe that perceptual differences in hearing, including pathological perturbations of our ability to accurately perceive our sensory environment, partly arise from variable circuitry...