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Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

Publication: Journal Article

Fruman, Mauvais-Jarvis, Pollard, Yballe, Brazil, Bronson, Kahn, and Cantley. 2000. “Hypoglycaemia, Liver Necrosis and Perinatal Death in Mice Lacking All Isoforms of Phosphoinositide 3-Kinase P85 Alpha”. Nat Genet 26 (3): 379-82.

Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells

Publication: Journal Article

Aspinwall, Qian, Roper, Kulkarni, Kahn, and Kennedy. 2000. “Roles of Insulin Receptor Substrate-1, Phosphatidylinositol 3-Kinase, and Release of Intracellular Ca2+ Stores in Insulin-Stimulated Insulin Secretion in Beta -Cells”. J Biol Chem 275 (29): 22331-8.

Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c-Fos gene

Publication: Journal Article

Brüning, Gillette, Zhao, Bjorbaeck, Kotzka, Knebel, Avci, et al. 2000. “Ribosomal Subunit Kinase-2 Is Required for Growth Factor-Stimulated Transcription of the C-Fos Gene”. Proc Natl Acad Sci U S A 97 (6): 2462-7.

Selective interaction between leptin and insulin signaling pathways in a hepatic cell line

Publication: Journal Article

Szanto, and Kahn. 2000. “Selective Interaction Between Leptin and Insulin Signaling Pathways in a Hepatic Cell Line”. Proc Natl Acad Sci U S A 97 (5): 2355-60.

The branch point enzyme of the mevalonate pathway for protein prenylation is overexpressed in the ob/ob mouse and induced by adipogenesis

Publication: Journal Article

Vicent, Maratos-Flier, and Kahn. 2000. “The Branch Point Enzyme of the Mevalonate Pathway for Protein Prenylation Is Overexpressed in the Ob/Ob Mouse and Induced by Adipogenesis”. Mol Cell Biol 20 (6): 2158-66.

Region-specific mRNA expression of phosphatidylinositol 3-kinase regulatory isoforms in the central nervous system of C57BL/6J mice

Publication: Journal Article

Hörsch, and Kahn. 1999. “Region-Specific MRNA Expression of Phosphatidylinositol 3-Kinase Regulatory Isoforms in the Central Nervous System of C57BL/6J Mice”. J Comp Neurol 415 (1): 105-20.

Postnatal growth responses to insulin-like growth factor I in insulin receptor substrate-1-deficient mice

Publication: Journal Article

Pete, Fuller, Oldham, DR Smith, D’Ercole, Kahn, and Lund. 1999. “Postnatal Growth Responses to Insulin-Like Growth Factor I in Insulin Receptor Substrate-1-Deficient Mice”. Endocrinology 140 (12): 5478-87.

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene

Publication: Journal Article

Araki, Lipes, Patti, Brüning, Haag, Johnson, and Kahn. 1994. “Alternative Pathway of Insulin Signalling in Mice With Targeted Disruption of the IRS-1 Gene”. Nature 372 (6502): 186-90.

Interactive roles of Ras, insulin receptor substrate-1, and proteins with Src homology-2 domains in insulin signaling in Xenopus oocytes

Publication: Journal Article

Chuang, Hausdorff, Myers, White, Birnbaum, and Kahn. 1994. “Interactive Roles of Ras, Insulin Receptor Substrate-1, and Proteins With Src Homology-2 Domains in Insulin Signaling in Xenopus Oocytes”. J Biol Chem 269 (44): 27645-9.

Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system

Publication: Journal Article

Folli, Bonfanti, Renard, Kahn, and Merighi. 1994. “Insulin Receptor Substrate-1 (IRS-1) Distribution in the Rat Central Nervous System”. J Neurosci 14 (11 Pt 1): 6412-22.