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NCI DCB Breast Cancer Awareness Month

News: October 27, 2023

NCI Division of Cancer Biology (DCB) highlighted Dr. Heng's DCB-supported breast cancer research on Twitter/X for Breast Cancer Awareness in October. https://x.com/NCICancerBio/status/1717988909551071461?s=20

Jackie Forbes

Person:

Jackie graduated from UMass Amherst with a BS in biology and minor in psychology. She recently joined the Parkinson’s Disease and Movement Disorders Center as a Clinical Research Assistant, where she contributes to a variety of PD clinical trials and patient programs. Her interests surround the role...

Research

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Research Overview Bone Biology Bone destruction commonly occurs in multiple rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis and lupus. In our laboratory, we study the molecular mechanisms that control osteoclast differentiation and activation, the cells that are primarily...

Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor.

Publication: Journal Article

Pilewski, Kelsey A, Steven Wall, Simone I Richardson, Nelia P Manamela, Kaitlyn Clark, Tandile Hermanus, Elad Binshtein, et al. 2023. “Functional HIV-1/HCV Cross-Reactive Antibodies Isolated from a Chronically Co-Infected Donor.”. Cell Reports 42 (2): 112044.

ABO blood group antigens and differential glycan expression: Perspective on the evolution of common human enzyme deficiencies.

Publication: Journal Article

Jajosky, Ryan Philip, Shang-Chuen Wu, Leon Zheng, Audrey N Jajosky, Philip G Jajosky, Cassandra D Josephson, Marie A Hollenhorst, et al. 2023. “ABO Blood Group Antigens and Differential Glycan Expression: Perspective on the Evolution of Common Human Enzyme Deficiencies.”. IScience 26 (1): 105798.

Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections.

Publication: Journal Article

Tamadonfar, Kevin O, Gisela Di Venanzio, Jerome S Pinkner, Karen W Dodson, Vasilios Kalas, Maxwell I Zimmerman, Jesus Bazan Villicana, Gregory R Bowman, Mario F Feldman, and Scott J Hultgren. 2023. “Structure-Function Correlates of Fibrinogen Binding by Acinetobacter Adhesins Critical in Catheter-Associated Urinary Tract Infections.”. Proceedings of the National Academy of Sciences of the United States of America 120 (4): e2212694120.

Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes.

Publication: Journal Article

Tran, Paul M H, Fran Dong, Eileen Kim, Katherine P Richardson, Lynn K H Tran, Kathleen Waugh, Diane Hopkins, et al. 2022. “Use of a Glycomics Array to Establish the Anti-Carbohydrate Antibody Repertoire in Type 1 Diabetes.”. Nature Communications 13 (1): 6527.

Computationally guided conversion of the specificity of E-selectin to mimic that of Siglec-8.

Publication: Journal Article

Wang, Xiaocong, Melinda S Hanes, Richard D Cummings, and Robert J Woods. 2022. “Computationally Guided Conversion of the Specificity of E-Selectin to Mimic That of Siglec-8.”. Proceedings of the National Academy of Sciences of the United States of America 119 (41): e2117743119.

The mannose receptor ligands and the macrophage glycome.

Publication: Journal Article

Cummings, Richard D. 2022. “The Mannose Receptor Ligands and the Macrophage Glycome.”. Current Opinion in Structural Biology 75: 102394.

Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes.

Publication: Web Article

Kashpur, Olga, Avi Smith, Behzad Gerami-Naini, Anna G Maione, Rossella Calabrese, Ana Tellechea, Georgios Theocharidis, et al. 2019. “Differentiation of Diabetic Foot Ulcer-Derived Induced Pluripotent Stem Cells Reveals Distinct Cellular and Tissue Phenotypes.”. 2019.