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Brown Fat and Cardiovascular Health

A Leducq Foundation Funded Network examining brown fat and cardiovascular health through genetic determinants and molecular mechanisms.

Brown adipose tissue is associated with healthier body fat distribution and metabolic benefits independent of regional adiposity.

Publication: Journal Article

Wibmer, Andreas G, Tobias Becher, Mahmoud Eljalby, Audrey Crane, Pamela Causa Andrieu, Caroline S Jiang, Roger Vaughan, Heiko Schöder, and Paul Cohen. 2021. “Brown Adipose Tissue Is Associated With Healthier Body Fat Distribution and Metabolic Benefits Independent of Regional Adiposity.”. Cell Reports: Medicine 2 (7): 100332.

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila.

Publication: Journal Article

Agrawal, Neha, Katherine Lawler, Catherine M Davidson, Julia M Keogh, Robert Legg, , Inês Barroso, Sadaf Farooqi, and Andrea H Brand. 2021. “Predicting Novel Candidate Human Obesity Genes and Their Site of Action by Systematic Functional Screening in Drosophila.”. PLoS Biology 19 (11): e3001255.

ER stress and Rho kinase activation underlie the vasculopathy of CADASIL.

Publication: Journal Article

Neves, Karla B, Adam P Harvey, Fiona Moreton, Augusto C Montezano, Francisco J Rios, Rheure Alves-Lopes, Aurelie Nguyen Dinh Cat, et al. 2019. “ER Stress and Rho Kinase Activation Underlie the Vasculopathy of CADASIL.”. JCI Insight 4 (23).

Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis.

Publication: Journal Article

Rios, Francisco J, Zhi-Guo Zou, Adam P Harvey, Katie Y Harvey, Ryszard Nosalski, Panagiota Anyfanti, Livia L Camargo, et al. 2020. “Chanzyme TRPM7 Protects Against Cardiovascular Inflammation and Fibrosis.”. Cardiovascular Research 116 (3): 721-35.

Programming human pluripotent stem cells into white and brown adipocytes.

Publication: Journal Article

Ahfeldt, Tim, Robert T Schinzel, Youn-Kyoung Lee, David Hendrickson, Adam Kaplan, David H Lum, Raymond Camahort, et al. 2012. “Programming Human Pluripotent Stem Cells into White and Brown Adipocytes.”. Nature Cell Biology 14 (2): 209-19.

Inaugural Collaborative Research Catalyst Award

News: June 02, 2020

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Jaylen Little

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Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers

Blog: April 21, 2023

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