Crosstalk Between Adipose and Lymphatics in Health and Disease.
Westcott, Gregory P, and Evan D Rosen. 2022. “Crosstalk Between Adipose and Lymphatics in Health and Disease.”. Endocrinology 163 (1).
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Regulation of early adipose commitment by Zfp521.
Kang, Sona, Peter Akerblad, Riku Kiviranta, Rana K Gupta, Shingo Kajimura, Michael J Griffin, Jie Min, Roland Baron, and Evan D Rosen. 2012. “Regulation of Early Adipose Commitment by Zfp521.”. PLoS Biology 10 (11): e1001433.
IRF4 is a key thermogenic transcriptional partner of PGC-1α.
Kong, Xingxing, Alexander Banks, Tiemin Liu, Lawrence Kazak, Rajesh R Rao, Paul Cohen, Xun Wang, et al. 2014. “IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α.”. Cell 158 (1): 69-83.
Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling.
Roh, Hyun Cheol, Manju Kumari, Solaema Taleb, Danielle Tenen, Christopher Jacobs, Anna Lyubetskaya, Linus T-Y Tsai, and Evan D Rosen. 2020. “Adipocytes Fail to Maintain Cellular Identity During Obesity Due to Reduced PPARγ Activity and Elevated TGFβ-SMAD Signaling.”. Molecular Metabolism 42: 101086.
Interferon regulatory factors are transcriptional regulators of adipogenesis.
Eguchi, Jun, Qing-Wu Yan, Dustin E Schones, Michael Kamal, Chung-Hsin Hsu, Michael Q Zhang, Gregory E Crawford, and Evan D Rosen. 2008. “Interferon Regulatory Factors Are Transcriptional Regulators of Adipogenesis.”. Cell Metabolism 7 (1): 86-94.
The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation.
Ahmad, Rasheed, Areej Al-Roub, Shihab Kochumon, Nadeem Akther, Reeby Thomas, Manju Kumari, Merin S Koshy, et al. 2018. “The Synergy Between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation.”. Journal of Immunology (Baltimore, Md. : 1950) 200 (10): 3599-3611.
Evan Rosen has received the Roy O. Greep Award for Outstanding Research
Established in 1944, the Endocrine Society’s Laureate Awards recognize the highest achievements in the endocrinology field, including groundbreaking research and innovations in clinical care. The Roy O. Greep Award for Outstanding Research recognizes meritorious contributions to research in...
Browser for a single cell atlas of human and mouse white adipose tissue
Data browser on the Broad Institutes Single Cell Portal and download links to Seurat objects of clusters and subclusters.