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DNA (CRISPR) gene modification and targeting in mouse embryos Embryonic Stem Cell Injections into mouse blastocysts for gene modification and targeting Embryo and Sperm Cryopreservation to bank novel mouse lines Line Rescue by IVF Line importation from cryopreserved sperm via IVF or embryos via...

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This section is for describing your available equipment and technologies.

Fluorescent Activated Cell Sorters ​ Beckman Coulter MoFlo AstriosEQ: A high-speed cell sorter (up to 70,000 cells/second) and analyzer (up to 100,000 cells/second), with four fixed lasers (405nm, 488nm, 561nm, and 640nm). The AstriosEQ has the capacity to acquire 28 parameters simultaneously. In...

We Specialize In Bulk and Single-Cell Transcriptomics and -omics RNA extraction, quality control, and library preparation for mRNA, total RNA, and single-cell/single-nuclei RNA-seq and -omics. For the latter, we also provide help with integration of single cell transcriptomic, epigenomic datasets...

The Core offers hands-on training, customized protocol development, and educational workshops in collaboration with partners across BIDMC, HMS, and the Harvard Chan Bioinformatics Core.

The CRC provides investigators with access to laboratory technicians for routine and complex sample processing. The laboratory processing staff has extensive experience in working with many central laboratories for federal and pharmaceutical company supported clinical research projects and with...

The nursing service of the Clinical Research Center at BIDMC is composed of registered nurses, medical assistants for research, and a certified sleep technician. CRC nurses implement the research study protocol, manage nursing care, and coordinate services throughout the research participant’s stay...