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Laboratoire BCGE Center for life Science 10th floor, 3 Blackfan St Boston, MA 02115 maid@bidmc.Harvard.edu (772) 501-7088

The Freedman Lab, a component of the Musculoskeletal Translation Innovation Initiative (MTII) at BIDMC, has a primary focus on pioneering innovative solutions to address unmet clinical needs within the musculoskeletal (MSK) domain. Our capabilities encompass a range of disciplines including...

Nuclei Isolation from human cortical tissue for enrichment of endothelial and microglial cells Click Here GitHub for scripts, data, and protocols

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We found that lin-4 mutants have short lifespans, while lin-4 over-expression extends lifespan and slows aging [1]. This was the first report of a role for miRNAs in regulating lifespan, and led to an intense study in my lab of roles for miRNAs in aging. Initially, we performed high throughput...