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The Friedman Lab studies the genetics of chronic kidney disease. We use human genetic and genomic studies to identify genetic variants important in kidney disease. We use mouse and cellular models to study these disease-associated variants using genetic, pharmacologic, biochemical, and molecular...
Functional connectivity associated with improvement in emotion management after cognitive enhancement therapy in early-course schizophrenia
Guimond, Synthia, George Ling, Jessica Drodge, Hannah Matheson, Jessica A. Wojtalik, Betzamel Lopez, Guusje Collin, et al. 2022. “Functional Connectivity Associated With Improvement in Emotion Management After Cognitive Enhancement Therapy in Early-Course Schizophrenia”. Psychological Medicine 52 (12): 2245-54.
Dynamic intervention-based biomarkers may reduce heterogeneity and motivate targeted interventions in clinical high risk for psychosis
Niznikiewicz, M.A., R.O. Brady, S. Whitfield-Gabrieli, M.S. Keshavan, T. Zhang, Li, O. Pasternak, M.E. Shenton, J. L. Wang, and W.S. Stone. 2022. “Dynamic Intervention-Based Biomarkers May Reduce Heterogeneity and Motivate Targeted Interventions in Clinical High Risk for Psychosis”. Schizophrenia Research 246: 60-62.
Dynamic and progressive changes in thalamic functional connectivity over the first five years of psychosis
Chan, Shi Yu, Roscoe O. Brady Jr., Kathryn E. Lewandowski, Amy Higgins, Dost Öngür, and Mei-Hua Hall. 2021. “Dynamic and Progressive Changes in Thalamic Functional Connectivity over the First Five Years of Psychosis”. Molecular Psychiatry 27: 1177-83.
Individual Variation in Functional Brain Network Topography is Linked to Schizophrenia Symptomatology
Nawaz, Uzma, Ivy Lee, Adan Beermann, Shaun M. Eack, Matcheri Keshavan, and Roscoe O. Brady Jr. 2020. “Individual Variation in Functional Brain Network Topography Is Linked to Schizophrenia Symptomatology”. Schizophrenia Bulletin 47 (1): 180-88.
Out-of-pocket prescription drug costs for adults with cardiovascular risk factors under Amazon's direct-to-consumer pharmacy service
Oddleifson, August, ZhaoNian Zheng, and Rishi K Wadhera. 2024. “Out-of-Pocket Prescription Drug Costs for Adults With Cardiovascular Risk Factors under Amazon’s Direct-to-Consumer Pharmacy Service”. Am Heart J. 271: 20-27.
Health Equity Adjustment and Hospital Performance in the Medicare Value-Based Purchasing Program
Liu, Michael, Sahil Sandhu, Karen E Joynt Maddox, and Rishi K Wadhera. 2024. “Health Equity Adjustment and Hospital Performance in the Medicare Value-Based Purchasing Program”. JAMA 331 (16): 1387-96.
Indirect impact of the war in Ukraine on primary percutaneous coronary interventions for ST-elevation myocardial infarction in Poland
Mamas, Mamas A., Glen P Martin, Marek Grygier, Rishi K Wadhera, Christian Mallen, Nick Curzen, Harindra C Wijeysundera, et al. 2024. “Indirect Impact of the War in Ukraine on Primary Percutaneous Coronary Interventions for ST-Elevation Myocardial Infarction in Poland”. Polish Archives of Internal Medicine.
Projected Changes in Statin and Antihypertensive Therapy Eligibility With the AHA PREVENT Cardiovascular Risk Equations
Diao, James A, Ivy Shi, Venkatesh L Murthy, Thomas A Buckley, Chirag J Patel, Emma Pierson, Robert W Yeh, Dhruv S Kazi, Rishi K Wadhera, and Arjun K Manrai. 2024. “Projected Changes in Statin and Antihypertensive Therapy Eligibility With the AHA PREVENT Cardiovascular Risk Equations”. JAMA.