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Clinical Proof-of-concept of a Novel Platform Utilizing Biopsy-derived Live Single Cells, Phenotypic Biomarkers, and Machine Learning Toward a Precision Risk Stratification Test for Prostate Cancer Grade Groups 1 and 2 (Gleason 3 + 3 and 3 + 4).

Publication: Journal Article

Albala, David, Michael S Manak, Jonathan S Varsanik, Hani H Rashid, Vladimir Mouraviev, Stephen M Zappala, Ene Ette, et al. 2019. “Clinical Proof-of-Concept of a Novel Platform Utilizing Biopsy-Derived Live Single Cells, Phenotypic Biomarkers, and Machine Learning Toward a Precision Risk Stratification Test for Prostate Cancer Grade Groups 1 and 2 (Gleason 3 + 3 and 3 + 4).”. Urology 124: 198-206.

Clinical validation of an epigenetic assay to predict negative histopathological results in repeat prostate biopsies.

Publication: Journal Article

Partin, Alan W, Leander Van Neste, Eric A Klein, Leonard S Marks, Jason R Gee, Dean A Troyer, Kimberly Rieger-Christ, et al. 2014. “Clinical Validation of an Epigenetic Assay to Predict Negative Histopathological Results in Repeat Prostate Biopsies.”. The Journal of Urology 192 (4): 1081-7.

A microRNA expression ratio defining the invasive phenotype in bladder tumors.

Publication: Journal Article

Neely, Lori A, Kimberly M Rieger-Christ, Brasil Silva Neto, Alexey Eroshkin, Joanne Garver, Sonal Patel, Nu Ai Phung, et al. 2010. “A MicroRNA Expression Ratio Defining the Invasive Phenotype in Bladder Tumors.”. Urologic Oncology 28 (1): 39-48.

The green tea compound, (-)-epigallocatechin-3-gallate downregulates N-cadherin and suppresses migration of bladder carcinoma cells.

Publication: Journal Article

Rieger-Christ, Kimberly M, Robert Hanley, Christopher Lodowsky, Trisha Bernier, Praneeth Vemulapalli, Mendel Roth, Jiyoung Kim, et al. 2007. “The Green Tea Compound, (-)-Epigallocatechin-3-Gallate Downregulates N-Cadherin and Suppresses Migration of Bladder Carcinoma Cells.”. Journal of Cellular Biochemistry 102 (2): 377-88.

The src-family kinase inhibitor PP2 suppresses the in vitro invasive phenotype of bladder carcinoma cells via modulation of Akt.

Publication: Journal Article

Chiang, George J, Brian R Billmeyer, David Canes, John Stoffel, Alireza Moinzadeh, Christina A Austin, Monika Kosakowski, Kimberly M Rieger-Christ, John A Libertino, and Ian C Summerhayes. 2005. “The Src-Family Kinase Inhibitor PP2 Suppresses the in Vitro Invasive Phenotype of Bladder Carcinoma Cells via Modulation of Akt.”. BJU International 96 (3): 416-22.

Histone deacetylase inhibitors upregulate plakoglobin expression in bladder carcinoma cells and display antineoplastic activity in vitro and in vivo.

Publication: Journal Article

Canes, David, George J Chiang, Brian R Billmeyer, Christina A Austin, Monika Kosakowski, Kimberly M Rieger-Christ, John A Libertino, and Ian C Summerhayes. 2005. “Histone Deacetylase Inhibitors Upregulate Plakoglobin Expression in Bladder Carcinoma Cells and Display Antineoplastic Activity in Vitro and in Vivo.”. International Journal of Cancer 113 (5): 841-8.

The HBP1 transcriptional repressor and the p38 MAP kinase: unlikely partners in G1 regulation and tumor suppression.

Publication: Journal Article

Yee, Amy S, Eric K Paulson, Michael A McDevitt, Kimberly Rieger-Christ, Ian Summerhayes, Stephen P Berasi, Jiyoung Kim, Chun-Yin Huang, and Xiaowei Zhang. 2004. “The HBP1 Transcriptional Repressor and the P38 MAP Kinase: Unlikely Partners in G1 Regulation and Tumor Suppression.”. Gene 336 (1): 1-13.

BIDMC Glycomics Core Launches SUGA for Rapid N-Glycan Profiling

News: January 05, 2026

Many biologically critical proteins such as viral surface proteins (including SARS-CoV-2 spike), antibodies, and cell-surface receptors are heavily glycosylated, and these sugars can profoundly influence protein function, stability, immune recognition, and drug response. A new Journal of Proteome...

MicroRNA spatial profiling for assessing drug efficacy in BRCA1-related triple-negative breast tumors

Publication: Journal Article

Mohd, Omar N, Lin Wang, Brian R Sardella, David Jou, Gerburg M Wulf, Frank J Slack, Yujing J Heng, and Patrick S Doyle. Submitted. “MicroRNA Spatial Profiling for Assessing Drug Efficacy in BRCA1-Related Triple-Negative Breast Tumors”. Submitted, Submitted.

Bedtime App-Guided Mindfulness Meditation in Patients With Insomnia: Mixed Methods Feasibility and Acceptability Pilot Study.

Publication: Journal Article

Ma, Yan, Peter M Wayne, Janet M Mullington, Suzanne Bertisch, and Gloria Y Yeh. 2025. “Bedtime App-Guided Mindfulness Meditation in Patients With Insomnia: Mixed Methods Feasibility and Acceptability Pilot Study.”. JMIR Formative Research 9: e67366.