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1766 results found

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

Publication: Journal Article

Fasshauer, Klein, Ueki, Kriauciunas, Benito, White, and Kahn. 2000. “Essential Role of Insulin Receptor Substrate-2 in Insulin Stimulation of Glut4 Translocation and Glucose Uptake in Brown Adipocytes”. J Biol Chem 275 (33): 25494-501.

Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts

Publication: Journal Article

Winnay, Brüning, Burks, and Kahn. 2000. “Gab-1-Mediated IGF-1 Signaling in IRS-1-Deficient 3T3 Fibroblasts”. J Biol Chem 275 (14): 10545-50.

Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies

Publication: Journal Article

Goldfine, AB, Patti, Zuberi, Goldstein, LeBlanc, Landaker, Jiang, Willsky, and Kahn. 2000. “Metabolic Effects of Vanadyl Sulfate in Humans With Non-Insulin-Dependent Diabetes Mellitus: In Vivo and in Vitro Studies”. Metabolism 49 (3): 400-10.

Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice

Publication: Journal Article

Gazdag, Dumke, Kahn, and Cartee. 1999. “Calorie Restriction Increases Insulin-Stimulated Glucose Transport in Skeletal Muscle from IRS-1 Knockout Mice”. Diabetes 48 (10): 1930-6.

Diabetes. Causes of insulin resistance

Publication: Journal Article

Kahn. 1995. “Diabetes. Causes of Insulin Resistance”. Nature 373 (6513): 384-5.

A mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation

Publication: Journal Article

Ouwens, Zon, Pronk, Bos, Möller, Cheatham, Kahn, and Maassen. 1994. “A Mutant Insulin Receptor Induces Formation of a Shc-Growth Factor Receptor Bound Protein 2 (Grb2) Complex and P21ras-GTP Without Detectable Interaction of Insulin Receptor Substrate 1 (IRS1) With Grb2. Evidence for IRS1-Independent P21ras-GTP Formation”. J Biol Chem 269 (52): 33116-22.

Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice

Publication: Journal Article

Ferber, Meyerovitch, Kriauciunas, and Kahn. 1994. “Vanadate Normalizes Hyperglycemia and Phosphoenolpyruvate Carboxykinase MRNA Levels in Ob/Ob Mice”. Metabolism 43 (11): 1346-54.

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

Publication: Journal Article

Kahn. 1994. “Banting Lecture. Insulin Action, Diabetogenes, and the Cause of Type II Diabetes”. Diabetes 43 (8): 1066-84.

Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus

Publication: Journal Article

Folli, Saad, Backer, and Kahn. 1993. “Regulation of Phosphatidylinositol 3-Kinase Activity in Liver and Muscle of Animal Models of Insulin-Resistant and Insulin-Deficient Diabetes Mellitus”. J Clin Invest 92 (4): 1787-94.

Two steps of insulin receptor internalization depend on different domains of the beta-subunit

Publication: Journal Article

Carpentier, Paccaud, Backer, Gilbert, Orci, Kahn, and Baecker J [corrected to Backer. 1993. “Two Steps of Insulin Receptor Internalization Depend on Different Domains of the Beta-Subunit”. J Cell Biol 122 (6): 1243-52.