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The effect of sodium oxybate (Xyrem ®) in a patient with laryngeal dystonia and voice tremor before (A) and after (B) drug intake (S imonyan K and Frucht SJ, Tremor Other Hyperkin Dis, 2013 ) Current treatment of laryngeal dystonia (LD) is limited to the temporary management of voice symptoms with...

POSTDOCTORAL FELLOWSHIP IN DECISION MODELING AND CANCER SURVIVORSHIP The Division of General Pediatrics at Boston Children’s Hospital is seeking a highly motivated and capable decision scientist, epidemiologist or outcomes researcher with a strong interest in cancer survivorship. The fellow will...

The Division of General Pediatrics at Boston Children’s Hospital is seeking a full-time Senior Scientist with a core competence in Quantitative Clinical Pharmacology and Pharmacokinetics and experience in laboratory management. The successful candidate will conduct and supervise assay development...

Until the approval of Luxturna®, there were no definitive treatments for any IRDs. Today, with the success of Luxturna®, preliminary results from therapies currently under investigation, and an expanding therapeutic toolkit, we have good reason for optimism. We envision a future in which gene...

Applications to Other Diseases The same types of genetic strategies currently being tested for IRDs are also being tested and beginning to receive regulatory approvals in other areas of medicine. For example, the FDA has approved both gene-augmentation therapy and antisense oligonucleotide therapy...

In this issue of eye Insights, we explore posterior uveitis and its varied etiologies. Inside, you’ll find common causes, tips for diagnosing posterior uveitis, and treatment techniques. Inside Message from Editor-in-Chief What is Posterior Uveitis Diagnosis Treatment Checkpoint Inhibitors Editor-in...

Treatment of Infectious Uveitis Treatment of infectious uveitis is dependent on the specific microbe. Treatment of Non-infectious Uveitis Anti-inflammatories Periocular, intravitreal, or systemic steroids are the mainstay of the acute treatment of non-infectious posterior uveitis. Topical steroids...