Search
Search results
126 results found
Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer's disease.
Yeganeh, Pourya Naderi, Sang Su Kwak, Mehdi Jorfi, Katjuša Koler, Thejesh Kalatturu, Djuna von Maydell, Zhiqing Liu, et al. 2025. “Integrative Pathway Analysis across Humans and 3D Cellular Models Identifies the P38 MAPK-MK2 Axis As a Therapeutic Target for Alzheimer’s Disease.”. Neuron 113 (2): 205-224.e8.
GCH1 Deficiency Activates Brain Innate Immune Response and Impairs Tyrosine Hydroxylase Homeostasis.
Larbalestier, Hannah, Marcus Keatinge, Lisa Watson, Emma White, Siri Gowda, Wenbin Wei, Katjuša Koler, et al. 2022. “GCH1 Deficiency Activates Brain Innate Immune Response and Impairs Tyrosine Hydroxylase Homeostasis.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 42 (4): 702-16.
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
Prokopenko, Dmitry, Sarah L Morgan, Kristina Mullin, Oliver Hofmann, Brad Chapman, Rory Kirchner, , et al. 2021. “Whole-Genome Sequencing Reveals New Alzheimer’s Disease-Associated Rare Variants in Loci Related to Synaptic Function and Neuronal Development.”. Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association 17 (9): 1509-27.
Aβ-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice.
Cuddy, Leah K, Dmitry Prokopenko, Eric P Cunningham, Ross Brimberry, Peter Song, Rory Kirchner, Brad A Chapman, et al. 2020. “Aβ-Accelerated Neurodegeneration Caused by Alzheimer’s-Associated ACE Variant R1279Q Is Rescued by Angiotensin System Inhibition in Mice.”. Science Translational Medicine 12 (563).
Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.
Prokopenko, Dmitry, Julian Hecker, Rory Kirchner, Brad A Chapman, Oliver Hoffman, Kristina Mullin, Winston Hide, et al. 2020. “Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.”. Scientific Reports 10 (1): 5029.
The Pathway Coexpression Network: Revealing pathway relationships.
Pita-Juárez, Yered, Gabriel Altschuler, Sokratis Kariotis, Wenbin Wei, Katjuša Koler, Claire Green, Rudolph E Tanzi, and Winston Hide. 2018. “The Pathway Coexpression Network: Revealing Pathway Relationships.”. PLoS Computational Biology 14 (3): e1006042.
Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives.
Daily, Kenneth, Shannan J Ho Sui, Lynn M Schriml, Phillip J Dexheimer, Nathan Salomonis, Robin Schroll, Stacy Bush, et al. 2017. “Molecular, Phenotypic, and Sample-Associated Data to Describe Pluripotent Stem Cell Lines and Derivatives.”. Scientific Data 4: 170030.
Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations.
Grasso, Carole, Matthew Anaka, Oliver Hofmann, Ramakrishna Sompallae, Kate Broadley, Winston Hide, Michael Berridge V, Jonathan Cebon, Andreas Behren, and Melanie J McConnell. 2016. “Iterative Sorting Reveals CD133+ and CD133- Melanoma Cells As Phenotypically Distinct Populations.”. BMC Cancer 16 (1): 726.
Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.
Roccaro, Aldo M, Antonio Sacco, Jiantao Shi, Marco Chiarini, Adriana Perilla-Glen, Salomon Manier, Siobhan Glavey, et al. 2016. “Exome Sequencing Reveals Recurrent Germ Line Variants in Patients With Familial Waldenström Macroglobulinemia.”. Blood 127 (21): 2598-606.