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CalR

Go to CalR, a web application for indirect calorimetry analysis. The CalR project: There is a critical lack of standardization for indirect calorimetry experiments to measure body composition ( Corrigan et al eLife 2020, Banks et al Nature Metabolism 2025). Currently, the same dataset can produce...

Body Composition Systems

EchoMRI 3-in-1 Body Composition Analyzer Measures live mice up to 100g, tissue samples (including Zebrafish) of 10g, and biopsy samples up to 0.1g Measurements include lean mass, fat mass, and water mass 5 minutes per mouse No anesthesia required

Optogenetic stimulation of food intake

Optogenetic stimulation of Agrp neurons in ChR2-expressing mice was performed in the Promethion calorimeter, with food intake, metabolic rate, body temperature, and activity measured during the stimulation period.

About Us

Beth Israel Deaconess Medical Center and Harvard Medical School - The home of CalR Energy Balance Metabolic Core at BIDMC and Harvard Medical School is a facility designed for the measurement of energy intake, nutritional status, and energy expenditure in experimental mice. This facility consists of...

Equipment and Technologies

Our facilities were updated and re-launched as an institutional Energy Balance Metabolic Core in 2019 to continue the tradition of excellence in metabolic research. This included a bomb calorimeter and a thermal imaging camera. In 2020 we obtained a Promethion indirect calorimeter and DSI’s...

Induction of torpor

C57Bl/6J female mice were monitored for body temperature and metabolic rate during the dark photoperiod without food, with the blue trace representing a fed mouse and the red trace a fasted mouse exhibiting torpor (Hrvatin et al., Nature, 2020).

Energy Balance Metabolic Core

Energy Balance Metabolic Core at BIDMC, measurement of energy intake, nutritional status, and energy expenditure in experimental mice