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345 results found

Genome-wide Study Identifies Association between HLA-B ∗ 55:01 and Self-Reported Penicillin Allergy

Publication: Journal Article

Krebs, Bovjin, Zheng, Lepamets, Censin, Jurgenson, Sarg, et al. 2020. “Genome-Wide Study Identifies Association Between HLA-B ∗ 55:01 and Self-Reported Penicillin Allergy”. American Journal of Human Genetics 107 (4): 612-21.

Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements

Publication: Journal Article

Amariuta, Ishigaki, Sugishita, Ohta, Koido, Dey, Matsuda, et al. 2020. “Improving the Trans-Ancestry Portability of Polygenic Risk Scores by Prioritizing Variants in Predicted Cell-Type-Specific Regulatory Elements”. Nature Genetics 52: 1346-54.

A framework for employing longitudinally collected multicenter electronic health records to stratify heterogeneous patient populations on disease history

Publication: Journal Article

Maurits, Marc, Ilya Korsunsky, Soumya Raychaudhuri, Shawn Murphy, Jordan Smoller, Scott Weiss, Thomas Huizinga, et al. 2022. “A Framework for Employing Longitudinally Collected Multicenter Electronic Health Records to Stratify Heterogeneous Patient Populations on Disease History”. J Am Med Inform Assoc 29 (5): 761-69.

TCR-sequencing in cancer and autoimmunity: barcodes and beyond

Publication: Journal Article

Pauken, Kristen, Kaitlyn Lagattuta, Benjamin Lu, Liliana Lucca, Adil Daud, David Hafler, Harriet Kluger, Soumya Raychaudhuri, and Arlene Sharpe. 2022. “TCR-Sequencing in Cancer and Autoimmunity: Barcodes and Beyond”. Trends Immunol 43 (3): 180-94.

Multimodal platform for assessing drug distribution and response in clinical trials

Publication: Journal Article

Lopez, Begoña, Ishwar Kohale, Ziming Du, Ilya Korsunsky, Walid Abdelmoula, Yang Dai, Sylwia Stopka, et al. 2022. “Multimodal Platform for Assessing Drug Distribution and Response in Clinical Trials”. Neuro Oncol 24 (1): 64-77.

Efficient and precise single-cell reference atlas mapping with Symphony

Publication: Journal Article

Kang, Nathan, Weinand, Zhang, Millard, Rumker, D. Branch Moody, Korsunsky, and Raychaudhuri. 2022. “Efficient and Precise Single-Cell Reference Atlas Mapping With Symphony”. Nature Communications 12 (5890).

HATK: HLA Analysis Toolkit

Publication: Journal Article

Choi, Luo, Raychaudhuri, and Han. 2021. “HATK: HLA Analysis Toolkit”. Bioinformatics 37 (3): 416-18.

Jessica Beynor

Person: MD/PhD Student, University of Colorado

Joseph Mears

Person: Bioinformatics Analyst II

Joyce Kang

Person: Harvard Medical School MD-PhD Student

I’m an MD/PhD student (MD though the Harvard/MIT HST program and PhD in Bioinformatics & Integrative Genomics). I joined the Raychaudhuri Lab in the summer of 2019 and am currently working on developing computational methods to efficiently map single-cell RNA-seq datasets against multi-million-cell...