Search

Po-Ru Loh has been awarded a 2019 Sloan Research Fellowship in Computational and Evolutionary Molecular Biology.

Po-Ru Loh will be presenting work on mosaic CNV detection using long-range phasing at the Broad Institute MIA Seminar on Wed 2/21 (with Giulio Genovese), the MIT Bioinformatics Seminar on Wed 2/21, and the UCLA Computational Genomics Winter Institute on Mon 2/26.

We are excited to share a new preprint, " Large mosaic copy number variations confer autism risk" (Sherman et al.), reporting mosaic CNVs we identified in genotyping data from the Simons Simplex Collection. We demonstrate a significant burden of large (>4 Mb) mosaic CNVs in ASD probands compared to...

This paper, " Mixed-model association for biobank-scale datasets" (Loh et al. 2018 Nat Genet), explores best practices for genome-wide association analyses in very large cohorts.

Po-Ru Loh has been awarded the International Society for Computational Biology's Overton Prize for outstanding accomplishment by an early to mid-career scientist in the field of computational biology. A big thank-you to all of the mentors, collaborators, and trainees who contributed to the work...

Our lab attended the Probabilistic Modeling in Genomics (ProbGen) 2021 virtual conference. Alison Barton and Maxwell Sherman spoke about their work on whole-exome imputation in UK Biobank (Alison) and deep-learning neutral somatic mutation rates in cancers (Max), and Margaux Hujoel and Ronen Mukamel...