Aristidis Veves

I am mainly involved in "bench to bedside" research. My main research field is diabetes and its complications, with the main emphasis on wound healing and cardiovascular disease. Approximately 90% of my effort is dedicated to research, 5% for teaching and an additional 5% for administrative and other relevant professional activities.

Translational research is a major part of my research activities. My work mainly focuses on the interaction between neuropathy and microvascular disease in the development of diabetic foot ulceration and the subsequent wound healing impairment. This work has been supported by NIH funding and nonprofit organizations. I collaborate with investigators from various departments of my hospital, the Beth Israel Deaconess Medical Center, and investigators from other institutions, such as the Brigham and Women's Hospital, to conduct additional translational research.

I conduct investigator-initiated research studies that are funded by the industry but have been conceived, designed and executed by my unit and focus on possible new mechanisms through which these medications exert their beneficial effects. Finally, in the past I have served as the leading investigator and the leading author in industry sponsored multicenter trials that investigated the efficacy of new therapeutic interventions for the management of diabetic foot ulceration.

I also run my own basic research laboratory that mainly explores the findings of the translational research and tries to identify mechanisms that are related to the observed results. My laboratory works closely with other laboratories in the Beth Israel Deaconess Medical Center and is funded by NIH grants. I also collaborate with established investigators in other institutions, such as Wyss Institute at Harvard University, Massachusetts Institute of Technology, Tufts Medical School, Boston University, Columbia University and University of Arkansas; the main aim of our collaboration is the development of new wound-healing products.  These collaborations have resulted in grants that are currently being funded by NIH and DARPA and DoD.

My research work has also resulted in awarded patents and submitted application patents.  It has also allowed the founding of a startup company (Epoulosis Therapeutics Inc.) that aims to produce new therapies for diabetic foot ulceration and diabetic neuropathy is based on these patents. 

The results of my research have been published in prestigious medical journals, including Lancet, Diabetes, Nature Biomedical Engineering and Nature Communications.   My work, according to Google Scholar as of November 2022, has resulted in more than 26,000 citations, an h index of 80 and i10-index of 187. 

I am also the founding Director of the Rongxiang Xu, MD Center for Regenerative Therapeutics since its establishment in December 2015.  The Center was established after a generous donation from the National Rongxiang Xu Foundation and its mission is to further advance the treatment of patients throughout the world with chronic wounds, burns, and other conditions resulting from a failure of tissue repair and regeneration. As part of its mission, the Center provides resources for the conduction of collaborative bench-to-bedside research with investigators worldwide and the education of physicians and scientists internationally regarding the management of the previously mentioned conditions.

Finally, I have served as consultant, member or Chairman in the Scientific Advisory boards of various companies.  This has provided me with unique understanding regarding the relationship between academia and industry that can lead to the development of new treatments for various conditions.

In summary, I am mainly involved in bench to bedside research regarding diabetes complications which includes collaborations from various departments of this institution and other institutions. My research is mainly funded by NIH and other nonprofit organizations while I also conduct investigator-initiated research funded by the industry. I also participate in teaching activities that mainly focus on the training of fellows and junior faculty.

Teaching, Training, and Education

My teaching responsibilities include participation in the training of the podiatry residents, supervision of the fellows and junior faculty in my lab and participation in mentorship committees of junior faculty members from other units. Finally, I participate as series editor, book editor or co-editor and author in numerous textbooks. One of these textbooks (Diabetes and Cardiovascular Disease) has been already translated to the Italian language and another one (Diabetic Foot) to the Greek and Chinese language.