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Beth Israel Deaconess Medical Center
George C. Tsokos
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PI3Kα in the pathogenesis and treatment of lupus nephritis.

Kasinath, V., & Tsokos, G. C. (2024). PI3Kα in the pathogenesis and treatment of lupus nephritis.. Kidney International.
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Last updated on 12/09/2024
PubMed

Recent Publications

  • Causation-based SLE diagnostic criteria should replace advance-repressing SLE classification criteria.
  • Mitochondrial dysfunction drives natural killer cell dysfunction in systemic lupus erythematosus.
  • Dysregulated soluble immune mediators and lupus-associated autoantibody specificities inform the development of immune indexes that characterise classified SLE transition and SLE disease activity.
  • Aberrant Glycosylation of IgG in Children With Active Lupus Nephritis Alters Podocyte Metabolism and Causes Podocyte Injury.
  • Aberrant T follicular helper cells generated by TH17 cell plasticity in the gut promote extraintestinal autoimmunity.
  • Advances in the treatment of systemic lupus erythematosus.
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Tsokos lab has focused on the cellular and molecular pathogenesis of systemic lupus erythematosus (SLE). Our laboratory has opened and led the field of molecular abnormalities on immune cells in patients with SLE.

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