Aging and the inflammatory, metabolic and autonomic response to sleep loss.

This project involved a testing of wake maintenance systems using a 64 hour vigil to challenge the inflammatory (measured in blood), metabolic (hormonal and glucose tolerance testing) and autonomic systems (catecholamine and blood pressure) to investigate whether the inflammatory response to sleep loss would increase with aging, particularly in the healthy elderly who were mildly to moderately overweight.

NIH/NIA AG28324-01 [PI: Janet M. Mullington] 8/1/2006 - 7/31/2010