Molecular Mechanisms of Brain Aging

Our previous research has shown that severe COVID-19 induces transcriptomic signatures in the human brain that resemble accelerated brain aging (Mavrikaki et al., 2022; Nature Aging). Funded by the National Institute on Aging (NIA), we are leveraging COVID-19 as a model of accelerated brain aging to uncover the molecular mechanisms driving both natural brain aging and COVID-19-induced accelerated aging. The ultimate goal of our research is to identify molecular targets to prevent, delay, or potentially reverse brain aging.

Learn more about the projects that lead us to continue exploring the molecular mechanisms of brain Aging!

Severe COVID could cause markers of old age in the brain

Severe COVID-19 linked with brain aging

COVID-19 and brain aging