In the Kaur Lab we conduct behavioral, biochemical, and electrophysiological studies in mouse models of apnea and pain, using novel genetic tools to selectively manipulate and record neural circuits involved in regulating neurobehavioral processes such as sleep, arousal, pain, breathing, and sleep homeostasis.
The Parabrachial Area in a Mouse
CGRP (Red) and FoxP2 (Green) neurons
Neural Circuits underlying waking up to Pain and Apnea
Highlighted Media and Publications
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Kaur S, Wang JL, Ferrari L, Thankachan S, Kroeger D, Venner A, Lazarus M, Wellman A, Arrigoni E, Fuller PM, Saper CB. A Genetically Defined Circuit for Arousal from Sleep during Hypercapnia. Neuron. 2017 Dec 6; 96(5):1153-1167.e5. PMCID: PMC5720904.
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Open ArchivePublished:November 02, 2017DOI:https://doi.org/10.1016/j.neuron.2017.10.009
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https://www.bidmc.org/about-bidmc/news/researchers-id-neurons-that-rouse-the-brain-to-breathe
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https://www.bidmc.org/about-bidmc/news/2020/07/selected-june-publications