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Our lab integrates multiple complementary approaches, including: genetic discovery in human cohorts, genome editing in zebrafish and human cell models, mass spectrometry–based metabolite profiling, and high-throughput screening of small-molecule libraries. We apply these strategies across several...

Mary Elizabeth Patti, M.D.

Dr. Patti’s NIH-funded laboratory studies are focused on identification of molecular and epigenetic mechanisms by which environmental/nutritional risk factors during early life confer risk for diabetes. Her laboratory utilizes cellular and animal models to study how insulin resistance and nutrition...