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Five Questions with Ai-ris Collier

News: October 05, 2021
Five Questions with Ai-ris Collier Our Postgraduate Education program alum discusses her research on the safety and effectiveness of administering COVID-19 mRNA vaccines to pregnant women. Ai-ris Collier, MD, is an instructor in obstetrics, gynecology, and reproductive biology at Beth Israel...

Ara Nazarian, PhD

Person: Lab Director
Associate Professor, Orthopaedic Surgery, Harvard Medical School Affiliated Associate Professor, Mechanical Engineering, Boston University I have had the pleasure of working with and mentoring over 170 undergraduate and graduate students and post-doctoral fellows from my early career days to date. I...

About the Lab

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My lab, along with the Saper group, is dedicated to advancing research in sleep and respiration, with a particular emphasis on the neural circuits involved in sleep, narcolepsy, sleep homeostasis, sleep deprivation, pain, and apnea-induced arousals. Our research employs state-of-the-art techniques...

Mapping Brainstem Control of Bladder Filling and Voiding

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Prior studies identify brain/spinal cord regions involved in controlling bladder function, but often do not resolve neuronal subpopulations or their specific connections. We seek to develop in mice a complete circuit map of the control of bladder filling and voiding. Prior work and our own...

Diet-induced obesity

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Analysis of diet-induced obesity experiments in male C57Bl/6J mice on a low-fat diet (LFD) or high-fat diet (HFD), demonstrating differences in body weight, energy intake, expenditure, and balance (Banks et al., Nature Metabolism, 2025). ​

Optogenetic stimulation of food intake

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Optogenetic stimulation of Agrp neurons in ChR2-expressing mice was performed in the Promethion calorimeter, with food intake, metabolic rate, body temperature, and activity measured during the stimulation period.

Research Area 1: Targeted Pathways for Diabetes Therapeutics

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Type 2 diabetes is one of obesity’s most tightly linked comorbidities, and its prevalence is rising in parallel with the global obesity epidemic. Uncontrolled obesity often leads to insulin resistance, beta cell failure, and hyperglycemia. Although effective, many glucose-lowering agents circumvent...