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We are honored to welcome Cecilia Cuilty Villarreal and Perla Alpizar Chacon who are joining us from Tecnológico de Monterrey for their undergraduate theses. We're excited to hear their ideas and collaborate with them on the development of their projects.

Employee Appreciation Day!

News: July 19, 2024

BIDMC hosted its employee appreciation day this past week, where the team enjoyed a team lunch, ice cream, and some summer sun!

Cecilia Cuilty Villarreal

Person: Undergraduate Student

Cecilia joined the lab in August of 2024 to conduct her undergraduate thesis. She is a Bioscience undergraduate student at Tecnológico de Monterrey. After obtaining her degree, she plans to pursue graduate studies with a focus in either neuroscience or drug development.

2024 Hypothalamus Gordon Research Conference

News: July 12, 2024

Dr. Machado will be presenting the lab's recent work on "A Brain Circuit for Energy Metabolism" at the 2024 Hypothalamus Gordon Research Conference! Dr. Machado's presentation will be given on the evening of Thursday, August 1st. This year's GRC Hypothalamus conference will be held July 28th-August...

EP3R-Expressing Glutamatergic Preoptic Neurons Mediate Inflammatory Fever

Publication: Journal Article

Machado, Natalia L.S., Sathyajit S. Bandaru, Stephen B.G. Abbott, and Clifford B. Saper. 2020. “EP3R-Expressing Glutamatergic Preoptic Neurons Mediate Inflammatory Fever”. Journal of Neuroscience 40 (12): 2573-88.

Machado Lab Harvard

Our goal is to produce knowledge for the development of novel therapeutic strategies and modulate body temperature for medicinal purposes.

Dr. Natalia Machado

Person: Assistant Professor in Neurology, Harvard Medical School, Staff Scientist, BIDMC

My research focuses on the underlying mechanisms by which the brain produces adaptive responses to physiological and behavioral stressors. During my Ph.D., I discovered that stress fever depends upon neurons in the dorsomedial nucleus of the hypothalamus that innervate medullary circuits for heat...

Dr. Luis Costa

Person: Postdoctoral Fellow

Luis obtained his Ph.D. in Neuroscience from the University of Sao Paulo, where he investigated the interaction between the immune system and the brain, and how this crosstalk modulates behavioral and endocrine alterations during inflammatory conditions such as sepsis. As a postdoctoral researcher...