Search

Search results

143 results found

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Publication: Journal Article

Warrington, Nicole, Robin Beaumont, Momoko Horikoshi, Felix Day, Øyvind Helgeland, Charles Laurin, Jonas Bacelis, et al. 2019. “Maternal and Fetal Genetic Effects on Birth Weight and Their Relevance to Cardio-Metabolic Risk Factors”. Nat Genet 51 (5): 804-14.

Protein-coding repeat polymorphisms strongly shape diverse human phenotypes

Publication: Journal Article

Mukamel, Ronen E, Robert Handsaker, Maxwell Sherman, Alison Barton, Yiming Zheng, Steven McCarroll, and Po-Ru Loh. 2021. “Protein-Coding Repeat Polymorphisms Strongly Shape Diverse Human Phenotypes”. Science 373 (6562): 1499-1505.

Estimating the effective sample size in association studies of quantitative traits

Publication: Journal Article

Ziyatdinov, Andrey, Jihye Kim, Dmitry Prokopenko, Florian Privé, Fabien Laporte, Po-Ru Loh, Peter Kraft, and Hugues Aschard. 2021. “Estimating the Effective Sample Size in Association Studies of Quantitative Traits”. G3 11 (6): jkab057.

Ronen E. Mukamel

Person: Instructor, Harvard Medical School

My current research focus is on structural variation in human genomes and the impact of structural variants on human health. My background is in pure mathematics, specifically the geometry of surfaces and billiards in polygons. When I am not engaged in research, I prefer to be walking up a mountain...

Nolan Kamitaki

Person: Ph.D. Student, Harvard Medical School Bioinformatics and Integrative Genomics (BIG)

Nolan is a PhD student in the Bioinformatics and Integrative Genomics (BIG) program at HMS. He previously studied statistics and computer science at Harvard University. His interests span the development and application of computational and molecular approaches to understanding how genetic variation...

Resources

Page

Hello world!

News: August 01, 2017

Po-Ru Loh has started a faculty position at Brigham and Women's Hospital / Harvard Medical School.

ASHG 2017 Epstein Award

News: October 26, 2017

Po-Ru Loh's plenary talk at ASHG 2017 won an Epstein Trainee Award for Excellence in Human Genetics!

Upcoming talks on phasing and mosaicism

News: October 08, 2018

Po-Ru Loh will be speaking about haplotype phasing and mosaic chromosomal alterations at 23andMe (Thu 10/11), ASHG 2018 (Wed 10/17, platform talk #17 at 9am), and Michigan (Tue 10/23).

Two new preprints on clonal hematopoiesis

News: May 31, 2019

We have released two preprints exploring mosaic chromosomal alterations in UK Biobank ( N~500K; Loh et al. bioRxiv) and BioBank Japan ( N~200K; Terao et al. bioRxiv). Highlights of these studies include discovery of several new risk loci at which acquired mutations systematically duplicate inherited...