Thrombospondins.
Lawler, Jack. 2008. “Thrombospondins.”. Current Drug Targets 9 (10): 820-1.
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Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan.
Chen, Faye Hui, Mary E Herndon, Nichlesh Patel, Jacqueline T Hecht, Rocky S Tuan, and Jack Lawler. 2007. “Interaction of Cartilage Oligomeric Matrix Protein/Thrombospondin 5 With Aggrecan.”. The Journal of Biological Chemistry 282 (34): 24591-8.
Vascular response to intra-arterial injury in the thrombospondin-1 null mouse.
Budhani, Faisal, Katherine A Leonard, Andreas Bergdahl, Jimin Gao, Jack Lawler, and Elaine C Davis. 2007. “Vascular Response to Intra-Arterial Injury in the Thrombospondin-1 Null Mouse.”. Journal of Molecular and Cellular Cardiology 43 (2): 210-4.
Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin.
Zhang, Xuefeng, Jianfeng Xu, Jack Lawler, Ernest Terwilliger, and Sareh Parangi. 2007. “Adeno-Associated Virus-Mediated Antiangiogenic Gene Therapy With Thrombospondin-1 Type 1 Repeats and Endostatin.”. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 13 (13): 3968-76.
Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).
Greenaway, James, Jack Lawler, Roger Moorehead, Paul Bornstein, Jonathan Lamarre, and Jim Petrik. 2007. “Thrombospondin-1 Inhibits VEGF Levels in the Ovary Directly by Binding and Internalization via the Low Density Lipoprotein Receptor-Related Protein-1 (LRP-1).”. Journal of Cellular Physiology 210 (3): 807-18.
Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13.
Bonnefoy, Arnaud, Kim Daenens, Hendrik B Feys, Rita De Vos, Petra Vandervoort, Jos Vermylen, Jack Lawler, and Marc F Hoylaerts. 2006. “Thrombospondin-1 Controls Vascular Platelet Recruitment and Thrombus Adherence in Mice by Protecting (sub)endothelial VWF from Cleavage by ADAMTS13.”. Blood 107 (3): 955-64.
Characterization of integrin beta6 and thrombospondin-1 double-null mice.
Ludlow, Anna, Karen O Yee, Ruth Lipman, R Bronson, P Weinreb, Xiaozhu Huang, D Sheppard, and J Lawler. 2005. “Characterization of Integrin Beta6 and Thrombospondin-1 Double-Null Mice.”. Journal of Cellular and Molecular Medicine 9 (2): 421-37.
Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors.
Sund, Malin, Yuki Hamano, Hikaru Sugimoto, Akulapalli Sudhakar, Mary Soubasakos, Udaya Yerramalla, Laura E Benjamin, et al. 2005. “Function of Endogenous Inhibitors of Angiogenesis As Endothelium-Specific Tumor Suppressors.”. Proceedings of the National Academy of Sciences of the United States of America 102 (8): 2934-9.
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis.
Christopherson, Karen S, Erik M Ullian, Caleb C A Stokes, Christine E Mullowney, Johannes W Hell, Azin Agah, Jack Lawler, Deane F Mosher, Paul Bornstein, and Ben A Barres. 2005. “Thrombospondins Are Astrocyte-Secreted Proteins That Promote CNS Synaptogenesis.”. Cell 120 (3): 421-33.
Activation of Latent TGF-β1 by Thrombospondin-1 is a Major Component of Wound Repair.
Nör, Jacques E, Luisa Dipietro, Joanne E Murphy-Ullrich, Richard O Hynes, Jack Lawler, and Peter J Polverini. 2005. “Activation of Latent TGF-β1 by Thrombospondin-1 Is a Major Component of Wound Repair.”. Oral Biosciences & Medicine : OBM 2 (2): 153-61.