Search

Search results

227 results found

Cobomarsen, an Oligonucleotide Inhibitor of miR-155, Slows DLBCL Tumor Cell Growth In Vitro and In Vivo.

Publication: Journal Article

Anastasiadou, Eleni, Anita G Seto, Xuan Beatty, Melanie Hermreck, Maud-Emmanuelle Gilles, Dina Stroopinsky, Lauren C Pinter-Brown, et al. 2021. “Cobomarsen, an Oligonucleotide Inhibitor of MiR-155, Slows DLBCL Tumor Cell Growth In Vitro and In Vivo.”. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 27 (4): 1139-49.

Photodestruction of Stromal Fibroblasts Enhances Tumor Response to PDT in 3D Pancreatic Cancer Coculture Models.

Publication: Journal Article

Karimnia, Vida, Imran Rizvi, Frank J Slack, and Jonathan P Celli. 2021. “Photodestruction of Stromal Fibroblasts Enhances Tumor Response to PDT in 3D Pancreatic Cancer Coculture Models.”. Photochemistry and Photobiology 97 (2): 416-26.

Ribosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegans.

Publication: Journal Article

Chan, Shih-Peng, and Frank J Slack. 2009. “Ribosomal Protein RPS-14 Modulates Let-7 MicroRNA Function in Caenorhabditis Elegans.”. Developmental Biology 334 (1): 152-60.

Inhibiting microRNA function in vivo.

Publication: Journal Article

Medina, Pedro P, and Frank J Slack. 2009. “Inhibiting MicroRNA Function in Vivo.”. Nature Methods 6 (1): 37-8.

The let-7 family of microRNAs.

Publication: Journal Article

Roush, Sarah, and Frank J Slack. 2008. “The Let-7 Family of MicroRNAs.”. Trends in Cell Biology 18 (10): 505-16.

The let-7 microRNA represses cell proliferation pathways in human cells.

Publication: Journal Article

Johnson, Charles D, Aurora Esquela-Kerscher, Giovanni Stefani, Mike Byrom, Kevin Kelnar, Dmitriy Ovcharenko, Mike Wilson, et al. 2007. “The Let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells.”. Cancer Research 67 (16): 7713-22.

Postdoctoral Research Fellows

Page

Latika Matai, PhD Latika is from New Delhi, India where she pursued her doctoral research studying aging, dietary restriction and stress responses using C. elegans as the model organism. She moved to United States in 2017 and later joined the Slack lab in 2019. She is interested in investigating the...

Graduate Students

Page

Tanvi Saxena (Harvard BBS Program) Tanvi grew up in New Delhi, India and graduated from the Indian Institute of Technology, Delhi with a B.Tech and M.Tech in Biochemical Engineering and Biotechnology. Having always been interested in the biological sciences and disease focused research, she worked...

LncRNA Dlx4os drives malignant transformation and phenotype switching in melanoma.

Publication: Journal Article

Ayub, Ana Luisa Pedroso, Beatriz Cristina Biz Tonin, Hátylas Azevedo, Pedro Henrique Fogaça Jordão, Tanvi Saxena, Leinal Sejour, Jeremie Nsengimana, et al. 2026. “LncRNA Dlx4os Drives Malignant Transformation and Phenotype Switching in Melanoma.”. Epigenetics 21 (1): 2641924.

MicroRNAs in Developmental Timing

Page

Our interest in miRNAs began with a desire to solve the fundamental question of how organs form at the right time during development [1, 4], and this core theme has since led us to a broader interest in the role of miRNAs in human disease and aging [5, 6]. We initially focused on using C. elegans to...