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Risk of wrist fracture, estimated by the load-to-strength ratio, declines following sleeve gastrectomy in adolescents and young adults.

Publication: Journal Article
Mitchell, Deborah M, Vibha Singhal, Supritha Nimmala, Meghan Lauze, Mary L Bouxsein, Madhusmita Misra, and Miriam A Bredella. 2024. “Risk of Wrist Fracture, Estimated by the Load-to-Strength Ratio, Declines Following Sleeve Gastrectomy in Adolescents and Young Adults.”. Osteoporosis International : A Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 35 (2): 285-91.

Long-duration type 1 diabetes is associated with deficient cortical bone mechanical behavior and altered matrix composition in human femoral bone.

Publication: Journal Article
Emerzian, Shannon R, Jarred Chow, Ramina Behzad, Mustafa Unal, Daniel J Brooks, I-Hsien Wu, John Gauthier, et al. 2024. “Long-Duration Type 1 Diabetes Is Associated With Deficient Cortical Bone Mechanical Behavior and Altered Matrix Composition in Human Femoral Bone.”. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research 40 (1): 87-99.

Micro-computed Tomography (uCT)

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Micro-computed tomography (microCT) is an imaging technique that uses x-rays to produce cross-sectional images of an object that can be reconstructed to create a three-dimensional model. It allows for non-destructive quantitative analysis of the density, geometry and microarchitecture of mineralized...

Reference Point Indentation (RPI)

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As part of our assessment of tissue properties, we perform microindentation using a BioDent tester, which is a novel reference point indentation device developed by ActiveLife Scientific. Reference Point Indentation enables assessment of bone material properties without requiring special surface...

Advanced imaging techniques for assessing skeletal fragility

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Osteoporosis remains underdiagnosed and undertreated. Current clinical standards have low sensitivity because half of all fracturesoccur in individuals without osteoporosis based on bone density testing and/or with few clinical risk factors. Photon-counting computed tomography (PCCT) is an emerging...

Associations of Muscle Strength and Functional Power with Longitudinal Change in HR-pQCT Bone Parameters: The Osteoporotic Fractures in Men (MrOS) Study.

Publication: Journal Article
Heilmann, Nina Z, Kerri S Freeland, Tong Yu, Paolo Caserotti, Andrew J Burghardt, Mary Winger Knueven, Bradley C Nindl, et al. 2025. “Associations of Muscle Strength and Functional Power With Longitudinal Change in HR-PQCT Bone Parameters: The Osteoporotic Fractures in Men (MrOS) Study.”. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research.