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567 results found

Abnormalities in spectrin structure and function in hereditary pyropoikilocytosis and hereditary elliptocytosis.

Publication: Journal Article

Lawler, J, S C Liu, A Street, and J Palek. 1984. “Abnormalities in Spectrin Structure and Function in Hereditary Pyropoikilocytosis and Hereditary Elliptocytosis.”. Progress in Clinical and Biological Research 159: 191-204.

Cooperative binding of calcium to thrombospondin. The effect of calcium on the circular dichroism and limited tryptic digestion of thrombospondin.

Publication: Journal Article

Lawler, J, and E R Simons. 1983. “Cooperative Binding of Calcium to Thrombospondin. The Effect of Calcium on the Circular Dichroism and Limited Tryptic Digestion of Thrombospondin.”. The Journal of Biological Chemistry 258 (20): 12098-101.

Thrombospondins in the tumor microenvironment.

Publication: Journal Article

Petrik, James, Sylvia Lauks, Bianca Garlisi, and Jack Lawler. 2024. “Thrombospondins in the Tumor Microenvironment.”. Seminars in Cell & Developmental Biology 155 (Pt B): 3-11.

Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer.

Publication: Journal Article

Matuszewska, Kathy, Lisa A Santry, Jacob P van Vloten, Amanda W K AuYeung, Pierre P Major, Jack Lawler, Sarah K Wootton, Byram W Bridle, and Jim Petrik. 2019. “Combining Vascular Normalization With an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer.”. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 25 (5): 1624-38.

Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer's disease.

Publication: Journal Article

Qin, Wei, Aihong Zhou, Xiumei Zuo, Longfei Jia, Fangyu Li, Qi Wang, Ying Li, et al. 2021. “Exome Sequencing Revealed PDE11A As a Novel Candidate Gene for Early-Onset Alzheimer’s Disease.”. Human Molecular Genetics 30 (9): 811-22.

Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.

Publication: Journal Article

Brase, Logan, Shih-Feng You, Ricardo D’Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, et al. 2023. “Single-Nucleus RNA-Sequencing of Autosomal Dominant Alzheimer Disease and Risk Variant Carriers.”. Nature Communications 14 (1): 2314.

Using global team science to identify genetic parkinson's disease worldwide.

Publication: Journal Article

Vollstedt, Eva-Juliane, Meike Kasten, Christine Klein, and MJFF Global Genetic Parkinson’s Disease Study Group. 2019. “Using Global Team Science to Identify Genetic Parkinson’s Disease Worldwide.”. Annals of Neurology 86 (2): 153-57.

Aging and injury affect nuclear shape heterogeneity in tendon

News: July 02, 2023

Congratulations to Dr. Ben Freedman and team on their new publication in the Journal of Orthopaedic Research! Check out the publication here.

Breakthrough treatments for accelerated wound healing

News: May 17, 2023

Congratulations to Dr. Ben Freedman and team for their review in Science Advances! Check out the review here.

Funding

Blog: January 18, 2024

The National Institutes of Health (NINDS, NIA) provides funding for projects in our lab. We are also sincerely grateful to the patients, family members, and caregivers who donated their time, brains, and biospecimens for biomedical research.