Seiya Oba, MD/PhD
I received my PhD degree from Tokyo Medical and Dental University, Japan. I started my work at the Tsokos lab in 2024. My research focuses on elucidating the role of CD38 in T cells in lupus.
Search
Search results
138 results found
Hyshem H. Lancia, PhD
My research focuses on advancing precision medicine for lupus nephritis by developing targeted nanodelivery systems that transport immune therapeutics directly to the kidneys.
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.
Xu, Meng, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P Hoefig, Christine Hohn, et al. 2024. “The Thymocyte-Specific RNA-Binding Protein Arpp21 Provides TCR Repertoire Diversity by Binding to the 3’-UTR and Promoting Rag1 MRNA Expression.”. Nature Communications 15 (1): 2194.
The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity.
Pan, Wenliang, Maria G Tsokos, Marc Scherlinger, Wei Li, and George C Tsokos. 2024. “The PP2A Regulatory Subunit PPP2R2A Controls NAD+ Biosynthesis to Regulate T cell Subset Differentiation in Systemic Autoimmunity.”. Cell Reports 43 (7): 114379.
Wenliang Pan, PhD
I obtained a PhD degree from the Chinese University of Hong Kong (CUHK) in Biomedical Sciences, Hong Kong. After that I join Tsokos lab for postdoctoral training. My current project are extensively involved in the study of the role of PP2A in the regulation of immune cell function including its role...
The emergence of SLE-causing UNC93B1 variants in 2024.
Tsokos, George C. 2024. “The Emergence of SLE-Causing UNC93B1 Variants in 2024.”. Nature Reviews. Rheumatology.
Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.
Rubio, Jose, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O’Connell, George C Tsokos, and Vasileios Kyttaris. 2024. “Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.”. ACR Open Rheumatology.
Curb complement to cure COVID-19
Satyam, A., and G. C. Tsokos. 2020. “Curb Complement to Cure COVID-19”. Clin Immunol 221: 108603.
TCR-alpha/beta CD4(-) CD8(-) double negative T cells arise from CD8(+) T cells
Rodriguez-Rodriguez, N., G. Flores-Mendoza, S. A. Apostolidis, F. Rosetti, G. C. Tsokos, and J. C. Crispin. 2020. “TCR-Alpha/Beta CD4(-) CD8(-) Double Negative T Cells Arise from CD8(+) T Cells”. J Leukoc Biol 108: 851-57.
Retraction Note: Microglia-dependent synapse loss in type I interferon-mediated lupus
Bialas, A. R., J. Presumey, A. Das, C. E. van der Poel, P. H. Lapchak, L. Mesin, G. Victora, et al. 2020. “Retraction Note: Microglia-Dependent Synapse Loss in Type I Interferon-Mediated Lupus”. Nature 578: 177.