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The Smith Center researchers discuss their work in Cardiology Outcomes in a series of videos below. Precision, Pragmatism & Parachutes: Modernizing Empiricism in Cardiovascular Care Dr. Robert Yeh describes strategies to improve the applicability of clinical trial results to cardiovascular care...

The pathomechanism of alcoholic liver disease (ALD) involves cumulative events such as leaky gut, hepatocyte damage and inflammation that collectively contribute to the severity of disease. Our studies have delineated the role of Toll-like receptor 4 (TLR4) signaling and identified a unique role for...

microRNAs in Alcoholic Liver Disease Alcoholic liver disease affects millions of people worldwide and it remains to be a therapeutic challenge for clinicians. Activation of the inflammatory cascade via gut-derived lipopolysaccharide (LPS) contributes to alcoholic liver disease via induction of pro...

Proper Citation Beth Israel Deaconess Medical Center - Preclinical Murine Pharmacogenetics Facility, RRID: SCR_026599 From an Idea to Its Realization An investigator has an idea for a new preclinical trial and takes it to Core Director for consultation. The Core Director provides advise in the study...